Apolipoprotein M promotes mobilization of cellular cholesterol in vivo

Sara Elsøe; Christina Christoffersen; Jayraz Luchoomun; Scott Turner; Lars Bo Nielsen

doi:10.1016/j.bbalip.2013.04.009

Apolipoprotein M promotes mobilization of cellular cholesterol in vivo

Sara Elsøe, Christina Christoffersen, Jayraz Luchoomun, Scott Turner, Lars Bo Nielsen

Physiology of circulation, kidney and lung

Research output: Contribution to journal › Journal article › Research › peer-review

32 Citations (Scopus)

Abstract

The HDL associated apolipoprotein M (apoM) protects against experimental atherosclerosis but the mechanism is unknown. ApoM increases prebeta-HDL formation. We explored whether plasma apoM affects mobilization of cholesterol from peripheral cells in mice.

Original language	English
Journal	Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids
Volume	1831
Issue number	7
Pages (from-to)	1287-92
Number of pages	6
ISSN	1388-1981
DOIs	https://doi.org/10.1016/j.bbalip.2013.04.009
Publication status	Published - Jul 2013

Keywords

Animals
Apolipoproteins
Atherosclerosis
Bile
Cell Line
Cholesterol
Feces
Foam Cells
Gene Deletion
Humans
Lipid Metabolism
Lipoproteins, HDL
Macrophages
Mice
Mice, Inbred C57BL
Mice, Transgenic

Access to Document

10.1016/j.bbalip.2013.04.009

Cite this

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title = "Apolipoprotein M promotes mobilization of cellular cholesterol in vivo",

abstract = "The HDL associated apolipoprotein M (apoM) protects against experimental atherosclerosis but the mechanism is unknown. ApoM increases prebeta-HDL formation. We explored whether plasma apoM affects mobilization of cholesterol from peripheral cells in mice.",

keywords = "Animals, Apolipoproteins, Atherosclerosis, Bile, Cell Line, Cholesterol, Feces, Foam Cells, Gene Deletion, Humans, Lipid Metabolism, Lipoproteins, HDL, Macrophages, Mice, Mice, Inbred C57BL, Mice, Transgenic",

author = "Sara Els{\o}e and Christina Christoffersen and Jayraz Luchoomun and Scott Turner and Nielsen, {Lars Bo}",

year = "2013",

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language = "English",

volume = "1831",

pages = "1287--92",

journal = "B B A - Molecular and Cell Biology of Lipids",

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TY - JOUR

T1 - Apolipoprotein M promotes mobilization of cellular cholesterol in vivo

AU - Elsøe, Sara

AU - Christoffersen, Christina

AU - Luchoomun, Jayraz

AU - Turner, Scott

AU - Nielsen, Lars Bo

PY - 2013/7

Y1 - 2013/7

N2 - The HDL associated apolipoprotein M (apoM) protects against experimental atherosclerosis but the mechanism is unknown. ApoM increases prebeta-HDL formation. We explored whether plasma apoM affects mobilization of cholesterol from peripheral cells in mice.

AB - The HDL associated apolipoprotein M (apoM) protects against experimental atherosclerosis but the mechanism is unknown. ApoM increases prebeta-HDL formation. We explored whether plasma apoM affects mobilization of cholesterol from peripheral cells in mice.

KW - Animals

KW - Apolipoproteins

KW - Atherosclerosis

KW - Bile

KW - Cell Line

KW - Cholesterol

KW - Feces

KW - Foam Cells

KW - Gene Deletion

KW - Humans

KW - Lipid Metabolism

KW - Lipoproteins, HDL

KW - Macrophages

KW - Mice

KW - Mice, Inbred C57BL

KW - Mice, Transgenic

U2 - 10.1016/j.bbalip.2013.04.009

DO - 10.1016/j.bbalip.2013.04.009

M3 - Journal article

C2 - 24046869

VL - 1831

SP - 1287

EP - 1292

JO - B B A - Molecular and Cell Biology of Lipids

JF - B B A - Molecular and Cell Biology of Lipids

SN - 1388-1981

IS - 7

ER -