TY - JOUR
T1 - Application of microdialysis technique in the traditional chinese medicine
AU - Zhang, Shaomin
AU - Zeng, Xianghui
AU - Xu, Xiaohong
AU - Zheng, Xiaoxiang
AU - grc540, grc540
PY - 2005
Y1 - 2005
N2 - The concentration of extracellular neurotransmitters can be dynamically measured by in vivo microdialysis. This technique can apply to quantitatively evaluating the beneficial effects of Traditional Chinese Medicine (TCM). In the present study, the protective effects of Puerarin (Pur) on cerebral injuries evoked by ischemia/reperfusion was supported by a decrease of extracellular amino acids, especially glutamate (Glu), which were monitored by microdialysis combined with HPLC throughout the experiments. It suggested that, in addition to being a versatile and practical method in neuroscience, the microdialysis technique would play an important role in assessing and screening the effects of TCM.
AB - The concentration of extracellular neurotransmitters can be dynamically measured by in vivo microdialysis. This technique can apply to quantitatively evaluating the beneficial effects of Traditional Chinese Medicine (TCM). In the present study, the protective effects of Puerarin (Pur) on cerebral injuries evoked by ischemia/reperfusion was supported by a decrease of extracellular amino acids, especially glutamate (Glu), which were monitored by microdialysis combined with HPLC throughout the experiments. It suggested that, in addition to being a versatile and practical method in neuroscience, the microdialysis technique would play an important role in assessing and screening the effects of TCM.
U2 - 10.1109/IEMBS.2005.1616303
DO - 10.1109/IEMBS.2005.1616303
M3 - Journal article
C2 - 17282072
SN - 1557-170X
VL - 7
SP - 7726
EP - 7729
JO - Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference
JF - Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference
ER -