Application of Ring Shear Testing to Optimize Pharmaceutical Formulation and Process Development of Solid Dosage Forms

Søren Vinter Søgaard, Troels Pedersen, Morten Allesø, Jørgen Garnæs, Jukka Rantanen

Research output: Contribution to conferencePaperResearchpeer-review

Abstract

This study investigates how shear and wall friction tests performed at small stresses can be applied to predict critical flow properties of powders, such as flow patterns and arching tendencies, in pharmaceutical manufacturing operations. The study showed that this approach is a promising method for pharmaceutical process development.
Original languageEnglish
Publication date12 Jun 2013
Number of pages7
Publication statusPublished - 12 Jun 2013
EventNordic Rheology Conference 2013 - University of Copenhagen, Copenhagen, Denmark
Duration: 12 Jun 201314 Jun 2013

Conference

ConferenceNordic Rheology Conference 2013
LocationUniversity of Copenhagen
Country/TerritoryDenmark
CityCopenhagen
Period12/06/201314/06/2013

Keywords

  • Faculty of Health and Medical Sciences
  • Shear testing
  • Powder blends
  • Flowabililty
  • Flow pattern
  • Solid dosage forms
  • Process development

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