Arabidopsis MKS1 is involved in basal immunity and requires an intact N-terminal domain for proper function

Klaus Petersen, Jin-Long Qiu, Juri Lütje, Berthe Katrine Fiil, Sidsel Hansen, John Mundy, Morten Petersen

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Abstract

Innate immune signaling pathways in animals and plants are regulated by mitogen-activated protein kinase (MAPK) cascades. MAP kinase 4 (MPK4) functions downstream of innate immune receptors via a nuclear substrate MKS1 to regulate the activity of the WRKY33 transcription factor, which in turn controls the production of anti-microbial phytoalexins.
Original languageEnglish
JournalP L o S One
Volume5
Issue number12
Pages (from-to)e14364
ISSN1932-6203
DOIs
Publication statusPublished - 1 Jan 2010

Keywords

  • Arabidopsis
  • Arabidopsis Proteins
  • Genotype
  • Immune System
  • MAP Kinase Signaling System
  • Microscopy, Confocal
  • Mitogen-Activated Protein Kinases
  • Mutagenesis, Site-Directed
  • Mutation
  • Phenotype
  • Phosphoproteins
  • Plant Physiological Phenomena
  • Plasmids
  • Protein Structure, Tertiary
  • Transcription Factors
  • Two-Hybrid System Techniques

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