Abstract
Innate immune signaling pathways in animals and plants are regulated by mitogen-activated protein kinase (MAPK) cascades. MAP kinase 4 (MPK4) functions downstream of innate immune receptors via a nuclear substrate MKS1 to regulate the activity of the WRKY33 transcription factor, which in turn controls the production of anti-microbial phytoalexins.
Original language | English |
---|---|
Journal | P L o S One |
Volume | 5 |
Issue number | 12 |
Pages (from-to) | e14364 |
ISSN | 1932-6203 |
DOIs | |
Publication status | Published - 1 Jan 2010 |
Keywords
- Arabidopsis
- Arabidopsis Proteins
- Genotype
- Immune System
- MAP Kinase Signaling System
- Microscopy, Confocal
- Mitogen-Activated Protein Kinases
- Mutagenesis, Site-Directed
- Mutation
- Phenotype
- Phosphoproteins
- Plant Physiological Phenomena
- Plasmids
- Protein Structure, Tertiary
- Transcription Factors
- Two-Hybrid System Techniques