Array-based genomic screening at diagnosis and during follow-up in chronic lymphocytic leukemia

Rebeqa Gunnarsson; Larry Mansouri; Anders Isaksson; Hanna Göransson; Nicola Cahill; Mattias Jansson; Markus Rasmussen; Jeanette De Sparra Lundin; Stefan Norin; Anne Mette Buhl; Karin Ekström Smedby; Henrik Hjalgrim; Karin Karlsson; Jesper Jurlander; Christian Geisler; Gunnar Juliusson; Richard Rosenquist

doi:10.3324/haematol.2010.039768

Array-based genomic screening at diagnosis and during follow-up in chronic lymphocytic leukemia

Rebeqa Gunnarsson, Larry Mansouri, Anders Isaksson, Hanna Göransson, Nicola Cahill, Mattias Jansson, Markus Rasmussen, Jeanette De Sparra Lundin, Stefan Norin, Anne Mette Buhl, Karin Ekström Smedby, Henrik Hjalgrim, Karin Karlsson, Jesper Jurlander, Christian Geisler, Gunnar Juliusson, Richard Rosenquist

Department of Clinical Medicine

Research output: Contribution to journal › Journal article › Research › peer-review

87 Citations (Scopus)

Abstract

High-resolution genomic microarrays enable simultaneous detection of copy-number aberrations such as the known recurrent aberrations in chronic lymphocytic leukemia [del(11q), del(13q), del(17p) and trisomy 12], and copy-number neutral loss of heterozygosity. Moreover, comparison of genomic profiles from sequential patients' samples allows detection of clonal evolution.

Original language	English
Journal	Haematologica
Volume	96
Issue number	8
Pages (from-to)	1161-9
Number of pages	9
ISSN	0390-6078
DOIs	https://doi.org/10.3324/haematol.2010.039768
Publication status	Published - 2011

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10.3324/haematol.2010.039768

Cite this

Gunnarsson, R., Mansouri, L., Isaksson, A., Göransson, H., Cahill, N., Jansson, M., Rasmussen, M., Lundin, J. D. S., Norin, S., Buhl, A. M., Smedby, K. E., Hjalgrim, H., Karlsson, K., Jurlander, J., Geisler, C., Juliusson, G., & Rosenquist, R. (2011). Array-based genomic screening at diagnosis and during follow-up in chronic lymphocytic leukemia. Haematologica, 96(8), 1161-9. https://doi.org/10.3324/haematol.2010.039768

Gunnarsson, R, Mansouri, L, Isaksson, A, Göransson, H, Cahill, N, Jansson, M, Rasmussen, M, Lundin, JDS, Norin, S, Buhl, AM, Smedby, KE, Hjalgrim, H, Karlsson, K, Jurlander, J, Geisler, C, Juliusson, G & Rosenquist, R 2011, 'Array-based genomic screening at diagnosis and during follow-up in chronic lymphocytic leukemia', Haematologica, vol. 96, no. 8, pp. 1161-9. https://doi.org/10.3324/haematol.2010.039768

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abstract = "High-resolution genomic microarrays enable simultaneous detection of copy-number aberrations such as the known recurrent aberrations in chronic lymphocytic leukemia [del(11q), del(13q), del(17p) and trisomy 12], and copy-number neutral loss of heterozygosity. Moreover, comparison of genomic profiles from sequential patients' samples allows detection of clonal evolution.",

author = "Rebeqa Gunnarsson and Larry Mansouri and Anders Isaksson and Hanna G{\"o}ransson and Nicola Cahill and Mattias Jansson and Markus Rasmussen and Lundin, {Jeanette De Sparra} and Stefan Norin and Buhl, {Anne Mette} and Smedby, {Karin Ekstr{\"o}m} and Henrik Hjalgrim and Karin Karlsson and Jesper Jurlander and Christian Geisler and Gunnar Juliusson and Richard Rosenquist",

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AU - Gunnarsson, Rebeqa

AU - Mansouri, Larry

AU - Isaksson, Anders

AU - Göransson, Hanna

AU - Cahill, Nicola

AU - Jansson, Mattias

AU - Rasmussen, Markus

AU - Lundin, Jeanette De Sparra

AU - Norin, Stefan

AU - Buhl, Anne Mette

AU - Smedby, Karin Ekström

AU - Hjalgrim, Henrik

AU - Karlsson, Karin

AU - Jurlander, Jesper

AU - Geisler, Christian

AU - Juliusson, Gunnar

AU - Rosenquist, Richard

PY - 2011

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AB - High-resolution genomic microarrays enable simultaneous detection of copy-number aberrations such as the known recurrent aberrations in chronic lymphocytic leukemia [del(11q), del(13q), del(17p) and trisomy 12], and copy-number neutral loss of heterozygosity. Moreover, comparison of genomic profiles from sequential patients' samples allows detection of clonal evolution.

U2 - 10.3324/haematol.2010.039768

DO - 10.3324/haematol.2010.039768

M3 - Journal article

SN - 0390-6078

VL - 96

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JO - Haematologica

JF - Haematologica

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ER -