Association between 8-oxo-7,8-dihydro-2'-deoxyguanosine excretion and risk of postmenopausal breast cancer: nested case-control study

Steffen Loft; Anja Olsen; Peter Møller; Henrik E Poulsen; Anne Tjønneland

doi:10.1158/1055-9965.EPI-13-0229

Association between 8-oxo-7,8-dihydro-2'-deoxyguanosine excretion and risk of postmenopausal breast cancer: nested case-control study

Steffen Loft, Anja Olsen, Peter Møller, Henrik E Poulsen, Anne Tjønneland

Research output: Contribution to journal › Journal article › Research › peer-review

62 Citations (Scopus)

Abstract

Oxidative stress may be important in carcinogenesis and a possible risk factor for breast cancer. The urinary excretion of oxidatively generated biomolecules, such as 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodG), represents biomarkers of oxidative stress, reflecting the rate of global damage to DNA in steady state.

Original language	English
Journal	Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Volume	22
Issue number	7
Pages (from-to)	1289-96
Number of pages	8
ISSN	1055-9965
DOIs	https://doi.org/10.1158/1055-9965.EPI-13-0229
Publication status	Published - Jul 2013

Keywords

Breast Neoplasms
Case-Control Studies
Cohort Studies
DNA Damage
Denmark
Deoxyguanosine
Diet
Female
Follow-Up Studies
Humans
Middle Aged
Oxidative Stress
Postmenopause
Prospective Studies
Receptors, Estrogen
Risk Factors
Tumor Markers, Biological

Access to Document

10.1158/1055-9965.EPI-13-0229

Cite this

Loft, S., Olsen, A., Møller, P., Poulsen, H. E., & Tjønneland, A. (2013). Association between 8-oxo-7,8-dihydro-2'-deoxyguanosine excretion and risk of postmenopausal breast cancer: nested case-control study. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 22(7), 1289-96. https://doi.org/10.1158/1055-9965.EPI-13-0229

Association between 8-oxo-7,8-dihydro-2'-deoxyguanosine excretion and risk of postmenopausal breast cancer : nested case-control study. / Loft, Steffen; Olsen, Anja; Møller, Peter ; Poulsen, Henrik E; Tjønneland, Anne.

In: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 22, No. 7, 07.2013, p. 1289-96.

Research output: Contribution to journal › Journal article › Research › peer-review

Loft, S, Olsen, A, Møller, P , Poulsen, HE & Tjønneland, A 2013, 'Association between 8-oxo-7,8-dihydro-2'-deoxyguanosine excretion and risk of postmenopausal breast cancer: nested case-control study', Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, vol. 22, no. 7, pp. 1289-96. https://doi.org/10.1158/1055-9965.EPI-13-0229

Loft S, Olsen A, Møller P , Poulsen HE, Tjønneland A. Association between 8-oxo-7,8-dihydro-2'-deoxyguanosine excretion and risk of postmenopausal breast cancer: nested case-control study. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2013 Jul;22(7):1289-96. https://doi.org/10.1158/1055-9965.EPI-13-0229

Loft, Steffen ; Olsen, Anja ; Møller, Peter ; Poulsen, Henrik E ; Tjønneland, Anne. / Association between 8-oxo-7,8-dihydro-2'-deoxyguanosine excretion and risk of postmenopausal breast cancer : nested case-control study. In: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2013 ; Vol. 22, No. 7. pp. 1289-96.

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