Abstract
Torsades de pointes arrhythmias (TdP) occur by definition in the setting of prolonged QT intervals. Animal models of drug induced Long-QT syndrome (dLQTS) have shown higher predictive value for proarrhythmia with beat-to-beat variability of repolarization duration (BVR) when compared with QT intervals. Here, we evaluate variability of QT intervals in patients with a history of drug-induced long QT syndrome (dLQTS) and TdP in absence of a mutation in any of the major LQTS genes.
Original language | English |
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Journal | European Heart Journal |
Volume | 29 |
Issue number | 2 |
Pages (from-to) | 185-90 |
Number of pages | 6 |
ISSN | 0195-668X |
DOIs | |
Publication status | Published - Jan 2008 |
Keywords
- Aged
- Arrhythmias, Cardiac
- Case-Control Studies
- Disease Susceptibility
- Electrocardiography
- Female
- Heart Rate
- Humans
- Long QT Syndrome
- Male
- Middle Aged
- Pilot Projects
- Predictive Value of Tests
- Torsades de Pointes