Biased Signaling of CCL21 and CCL19 Does Not Rely on N-Terminal Differences, but Markedly on the Chemokine Core Domains and Extracellular Loop 2 of CCR7

Astrid S. Jorgensen, Olav Larsen, Edith Uetz-von Allmen, Michael Lückmann, Daniel F. Legler, Thomas M. Frimurer, Christopher T. Veldkamp, Gertrud M. Hjortø, Mette M. Rosenkilde

Research output: Contribution to journalJournal articleResearchpeer-review

19 Citations (Scopus)
144 Downloads (Pure)
Original languageEnglish
Article number2156
JournalFrontiers in Immunology
Volume10
Number of pages14
ISSN1664-3224
DOIs
Publication statusPublished - 2019

Keywords

  • ligand biased signaling
  • CCR7
  • CCL21
  • CCL19
  • chemokine core domain
  • ECL2

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