Bioavailability of cinnarizine in dogs: effect of SNEDDS loading level and correlation with cinnarizine solubilization during in vitro lipolysis

Anne T Larsen, Pernilla Åkesson, Anna Juréus, Lasse Saaby, Ragheb Abu-Rmaileh, Bertil Abrahamsson, Jesper Østergaard, Anette Müllertz

Research output: Contribution to journalJournal articleResearchpeer-review

35 Citations (Scopus)

Abstract

To investigate the effect of increasing the loading level of the poorly soluble drug cinnarizine in a self-nanoemulsifying drug delivery system (SNEDDS) both in vitro and in vivo.
Original languageEnglish
JournalPharmaceutical Research
Volume30
Issue number12
Pages (from-to)3101-13
Number of pages13
ISSN0724-8741
DOIs
Publication statusPublished - Dec 2013

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