Bioenergetic modulation with dichloroacetate reduces the growth of melanoma cells and potentiates their response to BRAFV600E inhibition

Cecilie Abildgaard; Christina Dahl; Astrid Linde Basse; Tao Ma; Per Guldberg

doi:10.1186/s12967-014-0247-5

Bioenergetic modulation with dichloroacetate reduces the growth of melanoma cells and potentiates their response to BRAF^V600E inhibition

Cecilie Abildgaard, Christina Dahl, Astrid Linde Basse, Tao Ma, Per Guldberg

Genome Research and Molecular Bio Medicine

Research output: Contribution to journal › Journal article › Research › peer-review

36 Citations (Scopus)

1391 Downloads (Pure)

Original language	English
Article number	247
Journal	Journal of Translational Medicine
Volume	12
Number of pages	12
ISSN	1479-5876
DOIs	https://doi.org/10.1186/s12967-014-0247-5
Publication status	Published - 2014

Keywords

Dichloroacetate
Melanoma
BRAF
Bioenergetics
Metabolism
ATP

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10.1186/s12967-014-0247-5

Bioenergetic modulation with dichloroacetate reduces the growth of melanoma cells and potentiates their response to BRAFV600E inhibitionFinal published version, 2.35 MB

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Bioenergetic modulation with dichloroacetate reduces the growth of melanoma cells and potentiates their response to BRAF^V600E inhibition. / Abildgaard, Cecilie; Dahl, Christina; Basse, Astrid Linde; Ma, Tao; Guldberg, Per.

In: Journal of Translational Medicine, Vol. 12, 247, 2014.

Research output: Contribution to journal › Journal article › Research › peer-review

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AU - Basse, Astrid Linde

AU - Ma, Tao

AU - Guldberg, Per

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KW - Dichloroacetate

KW - Melanoma

KW - BRAF

KW - Bioenergetics

KW - Metabolism

KW - ATP

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DO - 10.1186/s12967-014-0247-5

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