TY - JOUR
T1 - Breast cancer survival and season of surgery
T2 - an ecological open cohort study
AU - Teilum, Dorthe
AU - Bjerre, Karsten D
AU - Tjønneland, Anne M
AU - Kroman, Niels
PY - 2012
Y1 - 2012
N2 - Background Vitamin D has been suggested to influence the incidence and prognosis of breast cancer, and studies have found better overall survival (OS) after diagnosis for breast cancer in summer-autumn, where the vitamin D level are expected to be highest. Objective To compare the prognostic outcome for early breast cancer patients operated at different seasons of the year. Design Open population-based cohort study. Setting Danish women operated 1978-2010. Cases 79 658 adjusted for age at surgery, period of surgery, tumour size, axillary lymph node status and hormone receptor status. Statistical analysis The association between OS and season of surgery was analysed by Cox proportional hazards regression models, at survival periods 0-1, 0-2, 0-5 and 0-10 years after surgery. A two-sided p value
AB - Background Vitamin D has been suggested to influence the incidence and prognosis of breast cancer, and studies have found better overall survival (OS) after diagnosis for breast cancer in summer-autumn, where the vitamin D level are expected to be highest. Objective To compare the prognostic outcome for early breast cancer patients operated at different seasons of the year. Design Open population-based cohort study. Setting Danish women operated 1978-2010. Cases 79 658 adjusted for age at surgery, period of surgery, tumour size, axillary lymph node status and hormone receptor status. Statistical analysis The association between OS and season of surgery was analysed by Cox proportional hazards regression models, at survival periods 0-1, 0-2, 0-5 and 0-10 years after surgery. A two-sided p value
U2 - 10.1136/bmjopen-2011-000358
DO - 10.1136/bmjopen-2011-000358
M3 - Journal article
C2 - 22223841
SN - 2044-6055
SN - 1756-1833
VL - 2
SP - e000358
JO - BMJ Open
JF - BMJ Open
ER -