C-reactive protein levels in relation to various features of non-alcoholic fatty liver disease among obese patients

Esther Zimmermann; Rodolphe Anty; Joan Tordjman; An Verrijken; Philippe Gual; Albert Tran; Antonio Iannelli; Jean Gugenheim; Pierre Bedossa; Sven Francque; Yannick Le Marchand-Brustel; Karine Clement; Luc Van Gaal; Thorkild I A Sørensen; Tine Jess

doi:10.1016/j.jhep.2010.12.017

C-reactive protein levels in relation to various features of non-alcoholic fatty liver disease among obese patients

Esther Zimmermann, Rodolphe Anty, Joan Tordjman, An Verrijken, Philippe Gual, Albert Tran, Antonio Iannelli, Jean Gugenheim, Pierre Bedossa, Sven Francque, Yannick Le Marchand-Brustel, Karine Clement, Luc Van Gaal, Thorkild I A Sørensen, Tine Jess

Department of Public Health

Research output: Contribution to journal › Journal article › Research › peer-review

99 Citations (Scopus)

Abstract

Non-alcoholic fatty liver disease (NAFLD) is a major hepatic consequence of obesity. It has been suggested that the high sensitivity C-reactive protein (hs-CRP) is an obesity-independent surrogate marker of severity of NAFLD, especially development of non-alcoholic steato-hepatitis (NASH), but this remains controversial. We aimed to investigate whether associations between various features of NAFLD and hs-CRP are independent of body mass index (BMI) in its broad range among obese patients.

Original language	English
Journal	Journal of Hepatology
Volume	55
Issue number	3
Pages (from-to)	660-5
Number of pages	6
ISSN	0168-8278
DOIs	https://doi.org/10.1016/j.jhep.2010.12.017 https://doi.org/10.1016/j.jhep.2010.12.017
Publication status	Published - 2011

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Zimmermann, E., Anty, R., Tordjman, J., Verrijken, A., Gual, P., Tran, A., Iannelli, A., Gugenheim, J., Bedossa, P., Francque, S., Le Marchand-Brustel, Y., Clement, K., Van Gaal, L., Sørensen, T. I. A., & Jess, T. (2011). C-reactive protein levels in relation to various features of non-alcoholic fatty liver disease among obese patients. Journal of Hepatology, 55(3), 660-5. https://doi.org/10.1016/j.jhep.2010.12.017, https://doi.org/10.1016/j.jhep.2010.12.017

Zimmermann, E, Anty, R, Tordjman, J, Verrijken, A, Gual, P, Tran, A, Iannelli, A, Gugenheim, J, Bedossa, P, Francque, S, Le Marchand-Brustel, Y, Clement, K, Van Gaal, L, Sørensen, TIA & Jess, T 2011, 'C-reactive protein levels in relation to various features of non-alcoholic fatty liver disease among obese patients', Journal of Hepatology, vol. 55, no. 3, pp. 660-5. https://doi.org/10.1016/j.jhep.2010.12.017, https://doi.org/10.1016/j.jhep.2010.12.017

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abstract = "Non-alcoholic fatty liver disease (NAFLD) is a major hepatic consequence of obesity. It has been suggested that the high sensitivity C-reactive protein (hs-CRP) is an obesity-independent surrogate marker of severity of NAFLD, especially development of non-alcoholic steato-hepatitis (NASH), but this remains controversial. We aimed to investigate whether associations between various features of NAFLD and hs-CRP are independent of body mass index (BMI) in its broad range among obese patients.",

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AU - Zimmermann, Esther

AU - Anty, Rodolphe

AU - Tordjman, Joan

AU - Verrijken, An

AU - Gual, Philippe

AU - Tran, Albert

AU - Iannelli, Antonio

AU - Gugenheim, Jean

AU - Bedossa, Pierre

AU - Francque, Sven

AU - Le Marchand-Brustel, Yannick

AU - Clement, Karine

AU - Van Gaal, Luc

AU - Sørensen, Thorkild I A

AU - Jess, Tine

PY - 2011

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N2 - Non-alcoholic fatty liver disease (NAFLD) is a major hepatic consequence of obesity. It has been suggested that the high sensitivity C-reactive protein (hs-CRP) is an obesity-independent surrogate marker of severity of NAFLD, especially development of non-alcoholic steato-hepatitis (NASH), but this remains controversial. We aimed to investigate whether associations between various features of NAFLD and hs-CRP are independent of body mass index (BMI) in its broad range among obese patients.

AB - Non-alcoholic fatty liver disease (NAFLD) is a major hepatic consequence of obesity. It has been suggested that the high sensitivity C-reactive protein (hs-CRP) is an obesity-independent surrogate marker of severity of NAFLD, especially development of non-alcoholic steato-hepatitis (NASH), but this remains controversial. We aimed to investigate whether associations between various features of NAFLD and hs-CRP are independent of body mass index (BMI) in its broad range among obese patients.

U2 - 10.1016/j.jhep.2010.12.017

DO - 10.1016/j.jhep.2010.12.017

M3 - Journal article

C2 - 21238518

SN - 0168-8278

VL - 55

SP - 660

EP - 665

JO - Journal of Hepatology

JF - Journal of Hepatology

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