Calcitonin gene-related peptide does not cause migraine attacks in patients with familial hemiplegic migraine

Jakob M Hansen; Lise L Thomsen; Jes Olesen; Messoud Ashina

doi:http://dx.doi.org/10.1111/j.1526-4610.2011.01861.x

Calcitonin gene-related peptide does not cause migraine attacks in patients with familial hemiplegic migraine

Jakob M Hansen, Lise L Thomsen, Jes Olesen, Messoud Ashina

Research output: Contribution to journal › Journal article › Research › peer-review

45 Citations (Scopus)

Abstract

Calcitonin gene-related peptide (CGRP) is a key molecule in migraine pathogenesis. Intravenous CGRP triggers migraine-like attacks in patients with migraine with aura and without aura. In contrast, patients with familial hemiplegic migraine (FHM) with known mutations did not report more migraine-like attacks compared to controls. Whether CGRP triggers migraine-like attacks in FHM patients without known mutations is unknown.

Original language	English
Journal	Headache
Volume	51
Issue number	4
Pages (from-to)	544-53
Number of pages	10
ISSN	0017-8748
DOIs	https://doi.org/10.1111/j.1526-4610.2011.01861.x
Publication status	Published - 2011

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http://dx.doi.org/10.1111/j.1526-4610.2011.01861.x

Cite this

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title = "Calcitonin gene-related peptide does not cause migraine attacks in patients with familial hemiplegic migraine",

abstract = "Calcitonin gene-related peptide (CGRP) is a key molecule in migraine pathogenesis. Intravenous CGRP triggers migraine-like attacks in patients with migraine with aura and without aura. In contrast, patients with familial hemiplegic migraine (FHM) with known mutations did not report more migraine-like attacks compared to controls. Whether CGRP triggers migraine-like attacks in FHM patients without known mutations is unknown.",

author = "Hansen, {Jakob M} and Thomsen, {Lise L} and Jes Olesen and Messoud Ashina",

note = "{\textcopyright} 2011 American Headache Society.",

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AU - Hansen, Jakob M

AU - Thomsen, Lise L

AU - Olesen, Jes

AU - Ashina, Messoud

PY - 2011

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AB - Calcitonin gene-related peptide (CGRP) is a key molecule in migraine pathogenesis. Intravenous CGRP triggers migraine-like attacks in patients with migraine with aura and without aura. In contrast, patients with familial hemiplegic migraine (FHM) with known mutations did not report more migraine-like attacks compared to controls. Whether CGRP triggers migraine-like attacks in FHM patients without known mutations is unknown.

U2 - http://dx.doi.org/10.1111/j.1526-4610.2011.01861.x

DO - http://dx.doi.org/10.1111/j.1526-4610.2011.01861.x

M3 - Journal article

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SP - 544

EP - 553

JO - Headache

JF - Headache

SN - 0017-8748

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