Calcium ion activity in physiological salt solutions: influence of anions substituted for chloride

Gert Rene Juul Christoffersen; Leif H Skibsted

doi:10.1016/S0300-9629(75)80094-6

Calcium ion activity in physiological salt solutions: influence of anions substituted for chloride

Gert Rene Juul Christoffersen, Leif H Skibsted

Research output: Contribution to journal › Journal article › Research › peer-review

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Abstract

1. Substitution by different anions for chloride in physiological salt solutions leads to binding between Ca²⁺ and the anion. Experiments designed to test effects of Cl^- therefore often show mixed effects of changes in Cl^- and Ca²⁺ activity.

2. This mixed effect is demonstrated in neurons of the snail, Helix pomatia: current-voltage characteristics and membrane potential are described during reduction of extracellular Cl^- using different anions as substitutes. Methylsulphate is concluded to be the best substitute in this preparation.

3. The association constants for the binding of Ca²⁺ to a number of anions is given.

Original language	English
Journal	Comparative Biochemistry and Physiology - Part A: Comparative Physiology
Volume	52
Issue number	2
Pages (from-to)	317-322
Number of pages	6
ISSN	0300-9629
DOIs	https://doi.org/10.1016/S0300-9629(75)80094-6
Publication status	Published - 1975

Bibliographical note

Key Word Index: Helix; nerve potentials; Calcium ions; methylsulphate; chloride

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title = "Calcium ion activity in physiological salt solutions: influence of anions substituted for chloride",

abstract = "1. Substitution by different anions for chloride in physiological salt solutions leads to binding between Ca2+ and the anion. Experiments designed to test effects of Cl- therefore often show mixed effects of changes in Cl- and Ca2+ activity. 2. This mixed effect is demonstrated in neurons of the snail, Helix pomatia: current-voltage characteristics and membrane potential are described during reduction of extracellular Cl- using different anions as substitutes. Methylsulphate is concluded to be the best substitute in this preparation.3. The association constants for the binding of Ca2+ to a number of anions is given.",

author = "Christoffersen, {Gert Rene Juul} and Skibsted, {Leif H}",

note = "Key Word Index: Helix; nerve potentials; Calcium ions; methylsulphate; chloride",

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T1 - Calcium ion activity in physiological salt solutions: influence of anions substituted for chloride

AU - Christoffersen, Gert Rene Juul

AU - Skibsted, Leif H

N1 - Key Word Index: Helix; nerve potentials; Calcium ions; methylsulphate; chloride

PY - 1975

Y1 - 1975

N2 - 1. Substitution by different anions for chloride in physiological salt solutions leads to binding between Ca2+ and the anion. Experiments designed to test effects of Cl- therefore often show mixed effects of changes in Cl- and Ca2+ activity. 2. This mixed effect is demonstrated in neurons of the snail, Helix pomatia: current-voltage characteristics and membrane potential are described during reduction of extracellular Cl- using different anions as substitutes. Methylsulphate is concluded to be the best substitute in this preparation.3. The association constants for the binding of Ca2+ to a number of anions is given.

AB - 1. Substitution by different anions for chloride in physiological salt solutions leads to binding between Ca2+ and the anion. Experiments designed to test effects of Cl- therefore often show mixed effects of changes in Cl- and Ca2+ activity. 2. This mixed effect is demonstrated in neurons of the snail, Helix pomatia: current-voltage characteristics and membrane potential are described during reduction of extracellular Cl- using different anions as substitutes. Methylsulphate is concluded to be the best substitute in this preparation.3. The association constants for the binding of Ca2+ to a number of anions is given.

U2 - 10.1016/S0300-9629(75)80094-6

DO - 10.1016/S0300-9629(75)80094-6

M3 - Journal article

SN - 0300-9629

VL - 52

SP - 317

EP - 322

JO - Comparative Biochemistry and Physiology - Part A: Comparative Physiology

JF - Comparative Biochemistry and Physiology - Part A: Comparative Physiology

IS - 2

ER -