TY - JOUR
T1 - Cathepsin X in serum from patients with colorectal cancer
T2 - relation to prognosis
AU - Vizin, Tjasa
AU - Christensen, Ib Jarle
AU - Nielsen, Hans Jørgen
AU - Kos, Janko
PY - 2012
Y1 - 2012
N2 - Up-regulation of lysosomal cysteine protease cathepsin X (Cat X) is associated with disorders of the immune system and neurodegenerative diseases, while its role in the development and progression of cancer is less understood. Enhanced secretion of pro-Cat X was observed in malignant processes, and therefore, the level of total serum Cat X rather than the active enzyme may better reflect the tumour status.
AB - Up-regulation of lysosomal cysteine protease cathepsin X (Cat X) is associated with disorders of the immune system and neurodegenerative diseases, while its role in the development and progression of cancer is less understood. Enhanced secretion of pro-Cat X was observed in malignant processes, and therefore, the level of total serum Cat X rather than the active enzyme may better reflect the tumour status.
U2 - 10.2478/v10019-012-0040-0
DO - 10.2478/v10019-012-0040-0
M3 - Journal article
C2 - 23077459
VL - 46
SP - 207
EP - 212
JO - Radiology and Oncology
JF - Radiology and Oncology
SN - 1318-2099
IS - 3
ER -