CDy14: A novel biofilm probe targeting exopolysaccharide Psl

Haw Young Kwon, Jun Young Kim, Jung Yeol Lee, Joey Kuok Hoong Yam, Louise Dahl Hultqvist, Wang Xu, Morten Rybtke, Tim Tolker-Nielsen, Jong Jin Kim, Nam Young Kang, Liang Yang, Sung Jin Park*, Michael Givskov, Young Tae Chang

*Corresponding author for this work

    Research output: Contribution to journalJournal articleResearchpeer-review

    8 Citations (Scopus)

    Abstract

    Detection of biofilm bacteria would be an ideal method for the physicians to diagnose chronic bacterial infections directly, but there are few imaging probes available so far. Here, we report the development of a novel biofilm detecting fluorescent probe, CDy14, through an unbiased screening of a fluorescence library and elucidated its binding partner Psl, an exopolysaccharide of the biofilm.

    Original languageEnglish
    JournalChemical Communications
    Volume54
    Issue number84
    Pages (from-to)11865-11868
    Number of pages4
    ISSN1359-7345
    DOIs
    Publication statusPublished - 2018

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