Combined Effect of the Preparation Method and Compression on the Physical Stability and Dissolution Behavior of Melt-Quenched Amorphous Celecoxib

Karlis Berzins, Sara J. Fraser-Miller, Rong Di, Jingwen Liu, Leena Peltonen, Clare J. Strachan, Thomas Rades, Keith C. Gordon

Research output: Contribution to journalJournal articleResearchpeer-review

7 Citations (Scopus)
26 Downloads (Pure)
Original languageEnglish
JournalMolecular Pharmaceutics
Volume18
Issue number3
Pages (from-to)1408-1418
ISSN1543-8384
DOIs
Publication statusPublished - 2021

Keywords

  • celecoxib
  • amorphous drugs
  • compression-induced destabilization
  • low-frequency Raman spectroscopy
  • dissolution

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