Computational redesign of thioredoxin is hypersensitive towards minor conformational changes in the backbone template

Kristoffer Enøe Johansson; Nicolai Tidemand Johansen; Signe Christensen; Scott Horowitz; James C. A.  Bardwell; Johan Gotthardt Olsen; Martin Willemoës; Kresten Lindorff-Larsen; Jesper Ferkinghoff-Borg; Thomas Wim Hamelryck; Jakob R. Winther

doi:10.1016/j.jmb.2016.09.013

Computational redesign of thioredoxin is hypersensitive towards minor conformational changes in the backbone template

Kristoffer Enøe Johansson, Nicolai Tidemand Johansen, Signe Christensen, Scott Horowitz, James C. A. Bardwell, Johan Gotthardt Olsen, Martin Willemoës, Kresten Lindorff-Larsen, Jesper Ferkinghoff-Borg, Thomas Wim Hamelryck, Jakob R. Winther

Research output: Contribution to journal › Journal article › Research › peer-review

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Original language	English
Journal	Journal of Molecular Biology
Volume	428
Issue number	21
Pages (from-to)	4361-4377
Number of pages	17
ISSN	0022-2836
DOIs	https://doi.org/10.1016/j.jmb.2016.09.013
Publication status	Published - 2016

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10.1016/j.jmb.2016.09.013

1-s2.0-S0022283616303783-mainAccepted author manuscript, 2.09 MB

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Johansson, K. E., Johansen, N. T., Christensen, S., Horowitz, S., Bardwell, J. C. A., Olsen, J. G., Willemoës, M., Lindorff-Larsen, K., Ferkinghoff-Borg, J., Hamelryck, T. W., & Winther, J. R. (2016). Computational redesign of thioredoxin is hypersensitive towards minor conformational changes in the backbone template. Journal of Molecular Biology, 428(21), 4361-4377. https://doi.org/10.1016/j.jmb.2016.09.013

Computational redesign of thioredoxin is hypersensitive towards minor conformational changes in the backbone template. / Johansson, Kristoffer Enøe ; Johansen, Nicolai Tidemand; Christensen, Signe; Horowitz, Scott; Bardwell, James C. A. ; Olsen, Johan Gotthardt ; Willemoës, Martin ; Lindorff-Larsen, Kresten; Ferkinghoff-Borg, Jesper; Hamelryck, Thomas Wim ; Winther, Jakob R.

In: Journal of Molecular Biology, Vol. 428, No. 21, 2016, p. 4361-4377.

Research output: Contribution to journal › Journal article › Research › peer-review

Johansson, KE , Johansen, NT, Christensen, S, Horowitz, S, Bardwell, JCA, Olsen, JG , Willemoës, M , Lindorff-Larsen, K, Ferkinghoff-Borg, J, Hamelryck, TW & Winther, JR 2016, 'Computational redesign of thioredoxin is hypersensitive towards minor conformational changes in the backbone template', Journal of Molecular Biology, vol. 428, no. 21, pp. 4361-4377. https://doi.org/10.1016/j.jmb.2016.09.013

Johansson, Kristoffer Enøe ; Johansen, Nicolai Tidemand ; Christensen, Signe ; Horowitz, Scott ; Bardwell, James C. A. ; Olsen, Johan Gotthardt ; Willemoës, Martin ; Lindorff-Larsen, Kresten ; Ferkinghoff-Borg, Jesper ; Hamelryck, Thomas Wim ; Winther, Jakob R. / Computational redesign of thioredoxin is hypersensitive towards minor conformational changes in the backbone template. In: Journal of Molecular Biology. 2016 ; Vol. 428, No. 21. pp. 4361-4377.

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author = "Johansson, {Kristoffer En{\o}e} and Johansen, {Nicolai Tidemand} and Signe Christensen and Scott Horowitz and Bardwell, {James C. A.} and Olsen, {Johan Gotthardt} and Martin Willemo{\"e}s and Kresten Lindorff-Larsen and Jesper Ferkinghoff-Borg and Hamelryck, {Thomas Wim} and Winther, {Jakob R.}",

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AU - Christensen, Signe

AU - Horowitz, Scott

AU - Bardwell, James C. A.

AU - Olsen, Johan Gotthardt

AU - Willemoës, Martin

AU - Lindorff-Larsen, Kresten

AU - Ferkinghoff-Borg, Jesper

AU - Hamelryck, Thomas Wim

AU - Winther, Jakob R.

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DO - 10.1016/j.jmb.2016.09.013

M3 - Journal article

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VL - 428

SP - 4361

EP - 4377

JO - Journal of Molecular Biology

JF - Journal of Molecular Biology

SN - 0022-2836

IS - 21

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