Continuous parenteral and enteral nutrition induces metabolic dysfunction in neonatal pigs

Barbara Stoll, Patrycja Jolanta Puiman, Liwei Cui, Xiaoyan Chang, Nancy Marie Benight, Caroline Bauchart-Thevret, Bolette Hartmann, Jens Juul Holst, Douglas Guy Burrin

Research output: Contribution to journalJournal articleResearchpeer-review

45 Citations (Scopus)

Abstract

We previously showed that parenteral nutrition (PN) compared with formula feeding results in hepatic insulin resistance and steatosis in neonatal pigs. The current aim was to test whether the route of feeding (intravenous [IV] vs enteral) rather than other feeding modalities (diet, pattern) had contributed to the outcome.
Original languageEnglish
JournalJournal of Parenteral and Enteral Nutrition
Volume36
Issue number5
Pages (from-to)538-50
Number of pages13
ISSN0148-6071
DOIs
Publication statusPublished - Sep 2012

Keywords

  • Administration, Intravenous
  • Animals
  • Animals, Newborn
  • Blood Glucose
  • Endpoint Determination
  • Enteral Nutrition
  • Fatty Liver
  • Female
  • Food, Formulated
  • Glucagon-Like Peptide 1
  • Glucagon-Like Peptide 2
  • Incretins
  • Inflammation
  • Insulin
  • Insulin Resistance
  • Intestine, Small
  • Liver
  • Metabolic Diseases
  • Nonlinear Dynamics
  • Organ Size
  • Parenteral Nutrition
  • Swine

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