Abstract
Several studies have found atrophy of the corpus callosum (CC) in patients with Alzheimer's disease (AD). However, it remains unclear whether callosal atrophy is already present in the early stages of AD, and to what extent it may be associated with other structural changes in the brain, such as age-related white matter changes (ARWMC) and progression of the disease.
Original language | English |
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Journal | Neurodegenerative Diseases |
Volume | 8 |
Issue number | 6 |
Pages (from-to) | 476-82 |
Number of pages | 7 |
ISSN | 1660-2854 |
DOIs | |
Publication status | Published - 2011 |
Keywords
- Aged
- Aged, 80 and over
- Alzheimer Disease
- Atrophy
- Brain
- Cognition Disorders
- Corpus Callosum
- Diagnostic and Statistical Manual of Mental Disorders
- Disease Progression
- Female
- Humans
- Image Processing, Computer-Assisted
- Logistic Models
- Magnetic Resonance Imaging
- Male
- Neuropsychological Tests
- Regression Analysis