Corpus callosum atrophy in patients with mild Alzheimer's disease

Kristian Steen Frederiksen, Ellen Garde, Arnold Skimminge, Charlotte Ryberg, Egill Rostrup, William F C Baaré, Hartwig R Siebner, Anne-Mette Hejl, Anne-Mette Leffers, Gunhild Waldemar

Research output: Contribution to journalJournal articleResearchpeer-review

41 Citations (Scopus)

Abstract

Several studies have found atrophy of the corpus callosum (CC) in patients with Alzheimer's disease (AD). However, it remains unclear whether callosal atrophy is already present in the early stages of AD, and to what extent it may be associated with other structural changes in the brain, such as age-related white matter changes (ARWMC) and progression of the disease.
Original languageEnglish
JournalNeurodegenerative Diseases
Volume8
Issue number6
Pages (from-to)476-82
Number of pages7
ISSN1660-2854
DOIs
Publication statusPublished - 2011

Keywords

  • Aged
  • Aged, 80 and over
  • Alzheimer Disease
  • Atrophy
  • Brain
  • Cognition Disorders
  • Corpus Callosum
  • Diagnostic and Statistical Manual of Mental Disorders
  • Disease Progression
  • Female
  • Humans
  • Image Processing, Computer-Assisted
  • Logistic Models
  • Magnetic Resonance Imaging
  • Male
  • Neuropsychological Tests
  • Regression Analysis

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