@article{5aa22ed049634591a3d96736a8c98219,
title = "Daily energy expenditure through the human life course",
abstract = "Total daily energy expenditure (“total expenditure”) reflects daily energy needs and is a critical variable in human health and physiology, but its trajectory over the life course is poorly studied. We analyzed a large, diverse database of total expenditure measured by the doubly labeled water method for males and females aged 8 days to 95 years. Total expenditure increased with fat-free mass in a power-law manner, with four distinct life stages. Fat-free mass-adjusted expenditure accelerates rapidly in neonates to ~50% above adult values at ~1 year; declines slowly to adult levels by ~20 years; remains stable in adulthood (20 to 60 years), even during pregnancy; then declines in older adults. These changes shed light on human development and aging and should help shape nutrition and health strategies across the life span.",
author = "Herman Pontzer and Yosuke Yamada and Hiroyuki Sagayama and Ainslie, {Philip N} and Andersen, {Lene F} and Anderson, {Liam J} and Lenore Arab and Issaad Baddou and Kweku Bedu-Addo and Blaak, {Ellen E} and Stephane Blanc and Bonomi, {Alberto G} and Bouten, {Carlijn V C} and Pascal Bovet and Buchowski, {Maciej S} and Butte, {Nancy F} and Camps, {Stefan G} and Close, {Graeme L} and Cooper, {Jamie A} and Richard Cooper and Das, {Sai Krupa} and Dugas, {Lara R} and Ulf Ekelund and Sonja Entringer and Terrence Forrester and Fudge, {Barry W} and Goris, {Annelies H} and Michael Gurven and Catherine Hambly and {El Hamdouchi}, Asmaa and Hoos, {Marjije B} and Sumei Hu and Noorjehan Joonas and Joosen, {Annemiek M} and Peter Katzmarzyk and Kempen, {Kitty P} and Misaka Kimura and Kraus, {William E} and Kushner, {Robert F} and Lambert, {Estelle V} and Leonard, {William R} and Nader Lessan and Corby Martin and Medin, {Anine C} and Meijer, {Erwin P} and Morehen, {James C} and Morton, {James P} and Neuhouser, {Marian L} and Sj{\"o}din, {Anders Mikael} and Wood, {Brian M} and {IAEA DLW Database Consortium}",
note = "Publisher Copyright: Copyright {\textcopyright} 2021 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works",
year = "2021",
doi = "10.1126/science.abe5017",
language = "English",
volume = "373",
pages = "808--812",
journal = "Science",
issn = "0036-8075",
publisher = "American Association for the Advancement of Science",
number = "6556",
}