@inproceedings{01756d4a3f344843b984b544acb2a3fa,
title = "Deep-Learning-Based Classification of Rat OCT Images After Intravitreal Injection of ET-1 for Glaucoma Understanding",
abstract = "Optical coherence tomography (OCT) is a useful technique to monitor retinal damage. We present an automatic method to accurately classify rodent OCT images in healthy and pathological (before and after 14 days of intravitreal injection of Endothelin-1, respectively) making use of the DenseNet-201 architecture fine-tuned and a customized top-model. We validated the performance of the method on 1912 OCT images yielding promising results in a leave-P-out cross-validation). Besides, we also compared the results of the fine-tuned network with those achieved training the network from scratch, obtaining some interesting insights. The presented method poses a step forward in understanding pathological rodent OCT retinal images, as at the moment there is no known discriminating characteristic which allows classifying this type of images accurately. The result of this work is a very accurate and robust automatic method to distinguish between healthy and a rodent model of glaucoma, which is the backbone of future works dealing with human OCT images.",
keywords = "Deep-learning, Glaucoma, Optical coherence tomography",
author = "F{\'e}lix Fuentes-Hurtado and Sandra Morales and Mossi, {Jose M.} and Valery Naranjo and Vadim Fedulov and David Woldbye and Kristian Klemp and Marie Torm and Michael Larsen",
year = "2018",
doi = "10.1007/978-3-030-03493-1_4",
language = "English",
isbn = "9783030034924",
series = "Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)",
publisher = "Springer",
pages = "27--34",
editor = "Hujun Yin and Paulo Novais and David Camacho and Tall{\'o}n-Ballesteros, {Antonio J.}",
booktitle = "Intelligent Data Engineering and Automated Learning – IDEAL 2018 - 19th International Conference, Proceedings",
address = "Switzerland",
note = "19th International Conference on Intelligent Data Engineering and Automated Learning, IDEAL 2018 ; Conference date: 21-11-2018 Through 23-11-2018",
}