Delivery of amitriptyline by intravenous and intraperitoneal administration compared in the same animal by whole-body mass spectrometry imaging of a stable isotope labelled drug substance in mice

Lois Morineau; Sophie Chakroun Jacobsen; Karen Kleberg; Harald S. Hansen; Christian Janfelt

doi:10.1080/17425247.2018.1541084

Delivery of amitriptyline by intravenous and intraperitoneal administration compared in the same animal by whole-body mass spectrometry imaging of a stable isotope labelled drug substance in mice

Lois Morineau, Sophie Chakroun Jacobsen, Karen Kleberg, Harald S. Hansen, Christian Janfelt

Research output: Contribution to journal › Journal article › Research › peer-review

8 Citations (Scopus)

Original language	English
Journal	Expert Opinion on Drug Delivery
Volume	15
Issue number	12
Pages (from-to)	1157-1163
ISSN	1742-5247
DOIs	https://doi.org/10.1080/17425247.2018.1541084
Publication status	Published - 2 Dec 2018

Keywords

Drug distribution
drug administration
mass spectrometry imaging
whole-body imaging
drug metabolism
DESI-MS

Access to Document

10.1080/17425247.2018.1541084

Cite this

Morineau, L., Jacobsen, S. C., Kleberg, K., Hansen, H. S., & Janfelt, C. (2018). Delivery of amitriptyline by intravenous and intraperitoneal administration compared in the same animal by whole-body mass spectrometry imaging of a stable isotope labelled drug substance in mice. Expert Opinion on Drug Delivery, 15(12), 1157-1163. https://doi.org/10.1080/17425247.2018.1541084

Delivery of amitriptyline by intravenous and intraperitoneal administration compared in the same animal by whole-body mass spectrometry imaging of a stable isotope labelled drug substance in mice. / Morineau, Lois; Jacobsen, Sophie Chakroun; Kleberg, Karen; Hansen, Harald S.; Janfelt, Christian.

In: Expert Opinion on Drug Delivery, Vol. 15, No. 12, 02.12.2018, p. 1157-1163.

Research output: Contribution to journal › Journal article › Research › peer-review

Morineau, L, Jacobsen, SC, Kleberg, K, Hansen, HS & Janfelt, C 2018, 'Delivery of amitriptyline by intravenous and intraperitoneal administration compared in the same animal by whole-body mass spectrometry imaging of a stable isotope labelled drug substance in mice', Expert Opinion on Drug Delivery, vol. 15, no. 12, pp. 1157-1163. https://doi.org/10.1080/17425247.2018.1541084

Morineau, Lois ; Jacobsen, Sophie Chakroun ; Kleberg, Karen ; Hansen, Harald S. ; Janfelt, Christian. / Delivery of amitriptyline by intravenous and intraperitoneal administration compared in the same animal by whole-body mass spectrometry imaging of a stable isotope labelled drug substance in mice. In: Expert Opinion on Drug Delivery. 2018 ; Vol. 15, No. 12. pp. 1157-1163.

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