Design and synthesis of novel Y-shaped barbituric acid derivatives as PPARγ activators

Vaibhav A. Dixit; Prakash Chandra Rathi; Shweta Bhagat; Holger Gohlke; Rasmus Koefoed Petersen; Karsten Kristiansen; Asit K. Chakraborti; Prasad V. Bharatam

doi:10.1016/j.ejmech.2015.11.030

Design and synthesis of novel Y-shaped barbituric acid derivatives as PPARγ activators

Vaibhav A. Dixit, Prakash Chandra Rathi, Shweta Bhagat, Holger Gohlke, Rasmus Koefoed Petersen, Karsten Kristiansen, Asit K. Chakraborti, Prasad V. Bharatam

Genome Research and Molecular Bio Medicine

Research output: Contribution to journal › Journal article › peer-review

22 Citations (Scopus)

Original language	English
Journal	European Journal of Medicinal Chemistry
Volume	108
Pages (from-to)	423-435
Number of pages	13
ISSN	0223-5234
DOIs	https://doi.org/10.1016/j.ejmech.2015.11.030
Publication status	Published - 2016

Keywords

Y-shaped ligands
PPAR gamma activation
Anti-diabetic agents
Barbituric acid derivatives
Competitive binding

Access to Document

10.1016/j.ejmech.2015.11.030

Cite this

Design and synthesis of novel Y-shaped barbituric acid derivatives as PPARγ activators. / Dixit, Vaibhav A.; Rathi, Prakash Chandra; Bhagat, Shweta; Gohlke, Holger; Petersen, Rasmus Koefoed; Kristiansen, Karsten; Chakraborti, Asit K.; Bharatam, Prasad V.

In: European Journal of Medicinal Chemistry, Vol. 108, 2016, p. 423-435.

Research output: Contribution to journal › Journal article › peer-review

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AU - Dixit, Vaibhav A.

AU - Rathi, Prakash Chandra

AU - Bhagat, Shweta

AU - Gohlke, Holger

AU - Petersen, Rasmus Koefoed

AU - Kristiansen, Karsten

AU - Chakraborti, Asit K.

AU - Bharatam, Prasad V.

PY - 2016

Y1 - 2016

KW - Y-shaped ligands

KW - PPAR gamma activation

KW - Anti-diabetic agents

KW - Barbituric acid derivatives

KW - Competitive binding

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DO - 10.1016/j.ejmech.2015.11.030

M3 - Journal article

C2 - 26708109

VL - 108

SP - 423

EP - 435

JO - European Journal of Medicinal Chemistry

JF - European Journal of Medicinal Chemistry

SN - 0223-5234

ER -