Design of excitatory amino acid receptor agonists, partial agonists and antagonists: Ibotenic acid as a key lead structure

P. Krogsgaard-Larsen; B. Ebert; Trine Meldgaard Lund; H. Bräuner-Osborne; F. A. Sloøk; T. N. Johansen; L. Brehm; U. Madsen

doi:10.1016/0223-5234(96)89549-3

Design of excitatory amino acid receptor agonists, partial agonists and antagonists: Ibotenic acid as a key lead structure

P. Krogsgaard-Larsen^*, B. Ebert, Trine Meldgaard Lund, H. Bräuner-Osborne, F. A. Sloøk, T. N. Johansen, L. Brehm, U. Madsen

^*Corresponding author for this work

Research output: Contribution to journal › Journal article › Research › peer-review

58 Citations (Scopus)

Original language	English
Journal	European Journal of Medicinal Chemistry
Volume	31
Issue number	7-8
Pages (from-to)	515-537
Number of pages	23
ISSN	0223-5234
DOIs	https://doi.org/10.1016/0223-5234(96)89549-3
Publication status	Published - 10 Sep 1996

Keywords

AMPA agonist
AMPA antagonist
AMPA partial agonist
AMPA receptor modulator
EAA and Alzheimer's disease
EAA and neurodegeneration
EAA and schizophrenia
Excitatory amino acid (EAA) receptor
Functional partial agonism
Glycine agonist
Glycine antagonist
Glycine partial agonist
Ionotropic EAA receptor
Kainic acid agonist
Kainic acid antagonist
Metabotropic EAA agonist
Metabotropic EAA antagonist
Metabotropic EAA receptor
NMDA agonist
NMDA antagonist
Receptor autoradiography

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10.1016/0223-5234(96)89549-3

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Cite this

Design of excitatory amino acid receptor agonists, partial agonists and antagonists : Ibotenic acid as a key lead structure. / Krogsgaard-Larsen, P.; Ebert, B.; Lund, Trine Meldgaard ; Bräuner-Osborne, H.; Sloøk, F. A.; Johansen, T. N.; Brehm, L.; Madsen, U.

In: European Journal of Medicinal Chemistry, Vol. 31, No. 7-8, 10.09.1996, p. 515-537.

Research output: Contribution to journal › Journal article › Research › peer-review

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T2 - Ibotenic acid as a key lead structure

AU - Krogsgaard-Larsen, P.

AU - Ebert, B.

AU - Lund, Trine Meldgaard

AU - Bräuner-Osborne, H.

AU - Sloøk, F. A.

AU - Johansen, T. N.

AU - Brehm, L.

AU - Madsen, U.

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KW - EAA and schizophrenia

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KW - Glycine agonist

KW - Glycine antagonist

KW - Glycine partial agonist

KW - Ionotropic EAA receptor

KW - Kainic acid agonist

KW - Kainic acid antagonist

KW - Metabotropic EAA agonist

KW - Metabotropic EAA antagonist

KW - Metabotropic EAA receptor

KW - NMDA agonist

KW - NMDA antagonist

KW - Receptor autoradiography

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DO - 10.1016/0223-5234(96)89549-3

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