Development of a definition for Rapid Progression (RP) of renal function in HIV-positive persons: the D:A:D study

David A Kamara, Lene Ryom Nielsen, Michael Ross, Ole Kirk, Peter Reiss, Philippe Morlat, Olivier Moranne, Christoph A Fux, Amanda Mocroft, Caroline Sabin, Jens D Lundgren, Colette J Smith

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Abstract

No consensus exists on how to define abnormally rapid deterioration in renal function (Rapid Progression, RP). We developed an operational definition of RP in HIV-positive persons with baseline estimated glomerular filtration rate (eGFR) >90ml/min/1.73m2 (using Cockcroft Gault) in the Data Collection on Adverse Events of Anti-HIV Drugs (D:A:D) study from 2004 to 2011.
Original languageEnglish
JournalB M C Nephrology
Volume15
Issue number1
Pages (from-to)1-13
Number of pages13
ISSN1471-2369
DOIs
Publication statusPublished - 25 Mar 2014

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