TY - JOUR
T1 - Diagnostic accuracy of expeditious bedside evaluation of cutaneous malignant melanoma using photoacoustic imaging
AU - von Knorring, Terese
AU - Blanche, Paul
AU - Holstad Pedersen, Helle
AU - Rosenkrantz Hölmich, Lisbet
AU - Løth Mårtensson, Nina
AU - Reichl, Charlène
AU - Karmisholt, Katrine
AU - Mogensen, Mette
N1 - Funding Information:
This study was funded by unrestricted grants from Vissing foundation, Axel Muusfeldt foundation, Toyota Foundation Denmark, Arvid Nilsson's foundation, NEYE foundation, Aase and Ejnar Danielsens foundation, Koebmand Sven Hansen & Hustru Ina Hansen's foundation and The Danish Cancer Society.
PY - 2024
Y1 - 2024
N2 - We study photoacoustic imaging (PAI) for diagnosing pigmented skin lesions. Clinical examination of nevi is challenging, leading to unnecessary skin biopsies. While dermoscopy improves accuracy, false positives remain high. PAI combines optical and ultrasound imaging by providing 3D images that visualize endogenous chromophores as melanin, haemoglobin, collagen and lipids at centimetre-depth. Reflectance confocal microscopy (RCM) offers in vivo cellular-level resolution improving diagnostic accuracy and demonstrating a 40% reduction in nevi excisions. By incorporating PAI alongside established methods, we aim to improve diagnostic precision.
AB - We study photoacoustic imaging (PAI) for diagnosing pigmented skin lesions. Clinical examination of nevi is challenging, leading to unnecessary skin biopsies. While dermoscopy improves accuracy, false positives remain high. PAI combines optical and ultrasound imaging by providing 3D images that visualize endogenous chromophores as melanin, haemoglobin, collagen and lipids at centimetre-depth. Reflectance confocal microscopy (RCM) offers in vivo cellular-level resolution improving diagnostic accuracy and demonstrating a 40% reduction in nevi excisions. By incorporating PAI alongside established methods, we aim to improve diagnostic precision.
U2 - 10.1111/jdv.20046
DO - 10.1111/jdv.20046
M3 - Letter
C2 - 38695655
AN - SCOPUS:85192158670
JO - Journal of the European Academy of Dermatology and Venereology
JF - Journal of the European Academy of Dermatology and Venereology
SN - 0926-9959
ER -