Direct Optical Detection of Singlet Oxygen from a Single Cell

Ingo Zebger; John W. Snyder; Lars Klembt Andersen; Lars Poulsen; Zhan Gao; John D.C. Lambert; Uffe Kristiansen; Peter R. Ogilby

doi:10.1562/RC-065R.1

Direct Optical Detection of Singlet Oxygen from a Single Cell

Ingo Zebger, John W. Snyder, Lars Klembt Andersen, Lars Poulsen, Zhan Gao, John D.C. Lambert, Uffe Kristiansen, Peter R. Ogilby^*

^*Corresponding author for this work

Molecular and Cellular Pharmacology

Research output: Contribution to journal › Journal article › Research › peer-review

60 Citations (Scopus)

Abstract

Singlet oxygen has been detected in single nerve cells by its weak 1270 nm phosphorescence (a¹Δ_g → Χ ³Σ_g^-) upon irradiation of a photosensitizer incorporated in the cell. Thus, one can now consider the application of direct optical imaging techniques to mechanistic studies of singlet oxygen at the single-cell level.

Original language	English
Journal	Photochemistry and Photobiology
Volume	79
Issue number	4
Pages (from-to)	319-322
Number of pages	4
ISSN	0031-8655
DOIs	https://doi.org/10.1562/RC-065R.1
Publication status	Published - Apr 2004

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title = "Direct Optical Detection of Singlet Oxygen from a Single Cell",

abstract = "Singlet oxygen has been detected in single nerve cells by its weak 1270 nm phosphorescence (a1Δg → Χ 3Σg-) upon irradiation of a photosensitizer incorporated in the cell. Thus, one can now consider the application of direct optical imaging techniques to mechanistic studies of singlet oxygen at the single-cell level.",

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AU - Zebger, Ingo

AU - Snyder, John W.

AU - Andersen, Lars Klembt

AU - Poulsen, Lars

AU - Gao, Zhan

AU - Lambert, John D.C.

AU - Kristiansen, Uffe

AU - Ogilby, Peter R.

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AB - Singlet oxygen has been detected in single nerve cells by its weak 1270 nm phosphorescence (a1Δg → Χ 3Σg-) upon irradiation of a photosensitizer incorporated in the cell. Thus, one can now consider the application of direct optical imaging techniques to mechanistic studies of singlet oxygen at the single-cell level.

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AN - SCOPUS:2342470771

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EP - 322

JO - Photochemistry and Photobiology

JF - Photochemistry and Photobiology

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Direct Optical Detection of Singlet Oxygen from a Single Cell

Abstract

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