TY - JOUR
T1 - Drugs That Changed Society
T2 - History and Current Status of the Early Antibiotics: Salvarsan, Sulfonamides, and β-Lactams
AU - Christensen, Søren Brøgger
PY - 2021
Y1 - 2021
N2 - The appearance of antibiotic drugs revolutionized the possibilities for treatment of diseases with high mortality such as pneumonia, sepsis, plaque, diphtheria, tetanus, typhoid fever, and tuberculosis. Today fewer than 1% of mortalities in high income countries are caused by diseases caused by bacteria. However, it should be recalled that the antibiotics were introduced in parallel with sanitation including sewerage, piped drinking water, high standard of living and improved understanding of the connection between food and health. Development of salvarsan, sulfonamides, and β-lactams into efficient drugs is described. The effects on life expectancy and life quality of these new drugs are indicated.
AB - The appearance of antibiotic drugs revolutionized the possibilities for treatment of diseases with high mortality such as pneumonia, sepsis, plaque, diphtheria, tetanus, typhoid fever, and tuberculosis. Today fewer than 1% of mortalities in high income countries are caused by diseases caused by bacteria. However, it should be recalled that the antibiotics were introduced in parallel with sanitation including sewerage, piped drinking water, high standard of living and improved understanding of the connection between food and health. Development of salvarsan, sulfonamides, and β-lactams into efficient drugs is described. The effects on life expectancy and life quality of these new drugs are indicated.
KW - Faculty of Health and Medical Sciences
KW - Society
KW - Antibiotics
KW - penicillin
KW - salvarsan
KW - Sulfonamide
KW - BETA-LACTAM ANTIBIOTICS
U2 - 10.3390/molecules26196057
DO - 10.3390/molecules26196057
M3 - Review
C2 - 34641601
VL - 26
JO - Molecules
JF - Molecules
SN - 1420-3049
IS - 19
M1 - 6057
ER -