TY - JOUR
T1 - Education, employment, and income among people living with cystic fibrosis across three decades
T2 - A matched cohort study using Danish health registries
AU - Jensen, Camilla Bjørn
AU - Jensen, Kristoffer Jarlov
AU - Pressler, Tacjana
AU - Katzenstein, Terese L.
AU - Skov, Marianne
AU - Qvist, Tavs
AU - Olsen, Mette Frahm
AU - Jeppesen, Majbritt
AU - Jensen-Fangel, Søren
AU - Olesen, Hanne Vebert
AU - Reuter, Simon Bertram
AU - Pedersen, Hans Kristian Råket
AU - Wang, Joanna Nan
AU - Michalopoulos, Steven
AU - McGarry, Lisa
AU - Wöhling, Heike
AU - Petersen, Janne
AU - Jimenez-Solem, Espen
AU - the TransformCF study group
N1 - Publisher Copyright:
© 2024
PY - 2024
Y1 - 2024
N2 - Background: Past and ongoing advancements in cystic fibrosis (CF) care warrant long-term analysis of the societal impact of the condition. This study aims to evaluate changes in key socioeconomic factors across three decades among people living with CF (pwCF), compared with both the general population and an early-onset chronic disease population. Methods: This nationwide, registry-based, matched cohort study included all pwCF ≥ 18 years in Denmark in the years 1990, 2000, 2010, and 2018. Each person living with CF was matched to five individuals in the general population and five individuals living with type 1 diabetes or juvenile arthritis based on age, sex, and municipality. Results: The Danish adult CF population increased nearly fourfold from 88 in 1990 to 331 in 2018, and mean age increased by ten years. The educational level of pwCF was similar to the two comparator cohorts, while pwCF were less often in employment and more often permanently outside the labor force. Personal and household income levels of the CF cohort were higher than those of the comparator cohorts. Conclusions: The disadvantage in employment for pwCF remained, but, over time, the societal profiles of the one-year CF cohorts increasingly converged with those of the comparator cohorts, indicative of improved clinical management, extended life expectancy, and the supportive role of the Danish welfare system in reducing health inequalities. Further research should be done to evaluate the effects of the newly introduced modulator therapies on employment, considering the broader societal impact and impact on quality of life.
AB - Background: Past and ongoing advancements in cystic fibrosis (CF) care warrant long-term analysis of the societal impact of the condition. This study aims to evaluate changes in key socioeconomic factors across three decades among people living with CF (pwCF), compared with both the general population and an early-onset chronic disease population. Methods: This nationwide, registry-based, matched cohort study included all pwCF ≥ 18 years in Denmark in the years 1990, 2000, 2010, and 2018. Each person living with CF was matched to five individuals in the general population and five individuals living with type 1 diabetes or juvenile arthritis based on age, sex, and municipality. Results: The Danish adult CF population increased nearly fourfold from 88 in 1990 to 331 in 2018, and mean age increased by ten years. The educational level of pwCF was similar to the two comparator cohorts, while pwCF were less often in employment and more often permanently outside the labor force. Personal and household income levels of the CF cohort were higher than those of the comparator cohorts. Conclusions: The disadvantage in employment for pwCF remained, but, over time, the societal profiles of the one-year CF cohorts increasingly converged with those of the comparator cohorts, indicative of improved clinical management, extended life expectancy, and the supportive role of the Danish welfare system in reducing health inequalities. Further research should be done to evaluate the effects of the newly introduced modulator therapies on employment, considering the broader societal impact and impact on quality of life.
KW - Cystic fibrosis
KW - Education
KW - Employment
KW - Income
U2 - 10.1016/j.jcf.2024.03.009
DO - 10.1016/j.jcf.2024.03.009
M3 - Journal article
C2 - 38485602
AN - SCOPUS:85188749643
VL - 23
SP - 836
EP - 841
JO - Journal of Cystic Fibrosis
JF - Journal of Cystic Fibrosis
SN - 1569-1993
IS - 5
ER -