Effect of glucagon-like peptide-1 on alpha- and beta-cell function in C-peptide-negative type 1 diabetic patients

Urd Kielgast, Meena Asmar, Sten Madsbad, Jens Juul Holst

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50 Citations (Scopus)

Abstract

The mechanism by which glucagon-like peptide-1 (GLP-1) suppresses glucagon secretion is uncertain, and it is not determined whether endogenous insulin is a necessary factor for this effect.
Original languageEnglish
JournalJournal of Clinical Endocrinology and Metabolism
Volume95
Issue number5
Pages (from-to)2492-6
Number of pages5
ISSN0021-972X
DOIs
Publication statusPublished - 2010

Keywords

  • Arginine
  • Blood Glucose
  • C-Peptide
  • Diabetes Mellitus, Type 1
  • Glucagon
  • Glucagon-Like Peptide 1
  • Glucagon-Secreting Cells
  • Humans
  • Hyperglycemia
  • Insulin-Secreting Cells
  • Serum Albumin

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