Effect of high-dose preoperative methylprednisolone on pain and recovery after total knee arthroplasty: a randomized, placebo-controlled trial

Troels Lunn; Billy Bjarne Kristensen; Lasse Andersen; H Husted; K S Otte; L Gaarn-Larsen; H Kehlet; Niels Kristian Stahl Otte; Henrik Kehlet

doi:10.1093/bja/aeq333

Effect of high-dose preoperative methylprednisolone on pain and recovery after total knee arthroplasty: a randomized, placebo-controlled trial

Troels Lunn, Billy Bjarne Kristensen, Lasse Andersen, H Husted, K S Otte, L Gaarn-Larsen, H Kehlet, Niels Kristian Stahl Otte, Henrik Kehlet

Research output: Contribution to journal › Journal article › Research › peer-review

223 Citations (Scopus)

Abstract

Total knee arthroplasty (TKA) is associated with severe pain and inflammation despite an extensive multimodal analgesic approach, but the effect of high-dose glucocorticoid administration has not been studied.

Original language	English
Journal	British Journal of Anaesthesia
Volume	106
Issue number	2
Pages (from-to)	230-8
Number of pages	8
ISSN	0007-0912
DOIs	https://doi.org/10.1093/bja/aeq333
Publication status	Published - 2011

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10.1093/bja/aeq333

Cite this

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title = "Effect of high-dose preoperative methylprednisolone on pain and recovery after total knee arthroplasty: a randomized, placebo-controlled trial",

abstract = "Total knee arthroplasty (TKA) is associated with severe pain and inflammation despite an extensive multimodal analgesic approach, but the effect of high-dose glucocorticoid administration has not been studied.",

author = "Troels Lunn and Kristensen, {Billy Bjarne} and Lasse Andersen and H Husted and Otte, {K S} and L Gaarn-Larsen and H Kehlet and Otte, {Niels Kristian Stahl} and Henrik Kehlet",

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T1 - Effect of high-dose preoperative methylprednisolone on pain and recovery after total knee arthroplasty: a randomized, placebo-controlled trial

AU - Lunn, Troels

AU - Kristensen, Billy Bjarne

AU - Andersen, Lasse

AU - Husted, H

AU - Otte, K S

AU - Gaarn-Larsen, L

AU - Kehlet, H

AU - Otte, Niels Kristian Stahl

AU - Kehlet, Henrik

PY - 2011

Y1 - 2011

N2 - Total knee arthroplasty (TKA) is associated with severe pain and inflammation despite an extensive multimodal analgesic approach, but the effect of high-dose glucocorticoid administration has not been studied.

AB - Total knee arthroplasty (TKA) is associated with severe pain and inflammation despite an extensive multimodal analgesic approach, but the effect of high-dose glucocorticoid administration has not been studied.

U2 - 10.1093/bja/aeq333

DO - 10.1093/bja/aeq333

M3 - Journal article

SN - 0007-0912

VL - 106

SP - 230

EP - 238

JO - British Journal of Anaesthesia

JF - British Journal of Anaesthesia

IS - 2

ER -