Effect of supersaturation on absorption of indomethacin and tadalafil in a single pass intestinal perfusion rat model, in the absence and presence of a precipitation inhibitor

Sophie Strindberg; Jakob Plum; Mai Bay Stie; Martin Lau Christiansen; Line Hagner Nielsen; Thomas Rades; Anette Mullertz

doi:10.1016/j.ejpb.2020.03.019

Effect of supersaturation on absorption of indomethacin and tadalafil in a single pass intestinal perfusion rat model, in the absence and presence of a precipitation inhibitor

Sophie Strindberg, Jakob Plum, Mai Bay Stie, Martin Lau Christiansen, Line Hagner Nielsen, Thomas Rades, Anette Mullertz

Research output: Contribution to journal › Journal article › Research › peer-review

15 Citations (Scopus)

Original language	English
Journal	European Journal of Pharmaceutics and Biopharmaceutics
Volume	151
Pages (from-to)	108-115
ISSN	0939-6411
DOIs	https://doi.org/10.1016/j.ejpb.2020.03.019
Publication status	Published - Jun 2020

Keywords

Intestinal perfusion
Precipitation
Absorption
Supersaturation
Oral drug delivery
Indomethacin
Tadalafil

Access to Document

10.1016/j.ejpb.2020.03.019

Cite this

Strindberg, S., Plum, J., Stie, M. B., Christiansen, M. L., Nielsen, L. H., Rades, T., & Mullertz, A. (2020). Effect of supersaturation on absorption of indomethacin and tadalafil in a single pass intestinal perfusion rat model, in the absence and presence of a precipitation inhibitor. European Journal of Pharmaceutics and Biopharmaceutics, 151, 108-115. https://doi.org/10.1016/j.ejpb.2020.03.019

Effect of supersaturation on absorption of indomethacin and tadalafil in a single pass intestinal perfusion rat model, in the absence and presence of a precipitation inhibitor. / Strindberg, Sophie; Plum, Jakob; Stie, Mai Bay; Christiansen, Martin Lau; Nielsen, Line Hagner; Rades, Thomas ; Mullertz, Anette.

In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 151, 06.2020, p. 108-115.

Research output: Contribution to journal › Journal article › Research › peer-review

Strindberg, S, Plum, J, Stie, MB, Christiansen, ML, Nielsen, LH, Rades, T & Mullertz, A 2020, 'Effect of supersaturation on absorption of indomethacin and tadalafil in a single pass intestinal perfusion rat model, in the absence and presence of a precipitation inhibitor', European Journal of Pharmaceutics and Biopharmaceutics, vol. 151, pp. 108-115. https://doi.org/10.1016/j.ejpb.2020.03.019

Strindberg S, Plum J, Stie MB, Christiansen ML, Nielsen LH, Rades T et al. Effect of supersaturation on absorption of indomethacin and tadalafil in a single pass intestinal perfusion rat model, in the absence and presence of a precipitation inhibitor. European Journal of Pharmaceutics and Biopharmaceutics. 2020 Jun;151:108-115. https://doi.org/10.1016/j.ejpb.2020.03.019

Strindberg, Sophie ; Plum, Jakob ; Stie, Mai Bay ; Christiansen, Martin Lau ; Nielsen, Line Hagner ; Rades, Thomas ; Mullertz, Anette. / Effect of supersaturation on absorption of indomethacin and tadalafil in a single pass intestinal perfusion rat model, in the absence and presence of a precipitation inhibitor. In: European Journal of Pharmaceutics and Biopharmaceutics. 2020 ; Vol. 151. pp. 108-115.

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