Effekten af cellebehandling hos patienter med kronisk iskæmisk hjertesygdom: en gennemgang af et Cochranereview

Anders Bruun Mathiasen; Abbas Ali Qayyum; Jens Kastrup

Effekten af cellebehandling hos patienter med kronisk iskæmisk hjertesygdom: en gennemgang af et Cochranereview

Translated title of the contribution: Effect of cell therapy in patients with chronic ischaemic heart disease--a survey of a Cochrane review

Anders Bruun Mathiasen, Abbas Ali Qayyum, Jens Kastrup

Department of Clinical Medicine

Research output: Contribution to journal › Review › peer-review

Abstract

The present Cochrane review included 23 studies randomized placebo-controlled clinical trials with a total of 1,255 patients. The effect of autologous cell therapy versus placebo was examined on left ventricular ejection fraction (LVEF), adverse effects and mortality in patients with chronic ischaemic heart disease. Patients treated with cell therapy had improved LVEF and functional status compared to patients who received placebo. There were no cell-related and only few procedure-related side effects. A positive effect of cell therapy on long-term survival was also demonstrated.

Translated title of the contribution	Effect of cell therapy in patients with chronic ischaemic heart disease--a survey of a Cochrane review
Original language	Danish
Journal	Ugeskrift for Laeger
Volume	177
Issue number	7
Pages (from-to)	642-44
Number of pages	3
ISSN	0041-5782
Publication status	Published - 30 Mar 2015

Access to Document

http://ugeskriftet.dk/videnskab/effekten-af-cellebehandling-hos-patienter-med-kronisk-iskaemisk-hjertesygdom-en-gennemgang

Library access?

Check availability at the Royal Danish Library

Cite this

@article{6a8353c6693b4c1593f2a64aca41f961,

title = "Effekten af cellebehandling hos patienter med kronisk isk{\ae}misk hjertesygdom: en gennemgang af et Cochranereview",

abstract = "The present Cochrane review included 23 studies randomized placebo-controlled clinical trials with a total of 1,255 patients. The effect of autologous cell therapy versus placebo was examined on left ventricular ejection fraction (LVEF), adverse effects and mortality in patients with chronic ischaemic heart disease. Patients treated with cell therapy had improved LVEF and functional status compared to patients who received placebo. There were no cell-related and only few procedure-related side effects. A positive effect of cell therapy on long-term survival was also demonstrated.",

author = "Mathiasen, {Anders Bruun} and {Ali Qayyum}, Abbas and Jens Kastrup",

year = "2015",

month = mar,

day = "30",

language = "Dansk",

volume = "177",

pages = "642--44",

journal = "Ugeskrift for Laeger",

issn = "0041-5782",

publisher = "Almindelige Danske Laegeforening",

number = "7",

}

TY - JOUR

T1 - Effekten af cellebehandling hos patienter med kronisk iskæmisk hjertesygdom

T2 - en gennemgang af et Cochranereview

AU - Mathiasen, Anders Bruun

AU - Ali Qayyum, Abbas

AU - Kastrup, Jens

PY - 2015/3/30

Y1 - 2015/3/30

N2 - The present Cochrane review included 23 studies randomized placebo-controlled clinical trials with a total of 1,255 patients. The effect of autologous cell therapy versus placebo was examined on left ventricular ejection fraction (LVEF), adverse effects and mortality in patients with chronic ischaemic heart disease. Patients treated with cell therapy had improved LVEF and functional status compared to patients who received placebo. There were no cell-related and only few procedure-related side effects. A positive effect of cell therapy on long-term survival was also demonstrated.

AB - The present Cochrane review included 23 studies randomized placebo-controlled clinical trials with a total of 1,255 patients. The effect of autologous cell therapy versus placebo was examined on left ventricular ejection fraction (LVEF), adverse effects and mortality in patients with chronic ischaemic heart disease. Patients treated with cell therapy had improved LVEF and functional status compared to patients who received placebo. There were no cell-related and only few procedure-related side effects. A positive effect of cell therapy on long-term survival was also demonstrated.

M3 - Review

C2 - 25697069

SN - 0041-5782

VL - 177

SP - 642

EP - 644

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 7

ER -