Trichuris suis ova therapy for allergic rhinitis does not affect allergen-specific cytokine responses despite a parasite-specific cytokine response

C.D. Bourke; F. Mutapi; N. Nausch; D.M.F. Photiou; Lars K. Poulsen; B. Kristensen; J. Arnved; S. Rønborg; Allan Knud Roepstorff; Stig Milan Thamsborg; Christian Moliin Outzen Kapel; Martin Melbye; Palle Bager

doi:10.1111/j.1365-2222.2012.04063.x

Trichuris suis ova therapy for allergic rhinitis does not affect allergen-specific cytokine responses despite a parasite-specific cytokine response

C.D. Bourke, F. Mutapi, N. Nausch, D.M.F. Photiou, Lars K. Poulsen, B. Kristensen, J. Arnved, S. Rønborg, Allan Knud Roepstorff, Stig Milan Thamsborg, Christian Moliin Outzen Kapel, Martin Melbye, Palle Bager

Research output: Contribution to journal › Journal article › Research › peer-review

26 Citations (Scopus)

Abstract

Parasitic helminths have been shown to reduce inflammation in most experimental models of allergic disease, and this effect is mediated via cytokine responses. However, in humans, the effects of controlled helminth infection on cytokine responses during allergy have not been studied.

Original language	English
Journal	Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
Volume	42
Issue number	11
Pages (from-to)	1582-1595
Number of pages	14
DOIs	https://doi.org/10.1111/j.1365-2222.2012.04063.x
Publication status	Published - 2012

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10.1111/j.1365-2222.2012.04063.x

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Bourke, C. D., Mutapi, F., Nausch, N., Photiou, D. M. F., Poulsen, L. K., Kristensen, B., Arnved, J., Rønborg, S., Roepstorff, A. K., Thamsborg, S. M., Kapel, C. M. O., Melbye, M., & Bager, P. (2012). Trichuris suis ova therapy for allergic rhinitis does not affect allergen-specific cytokine responses despite a parasite-specific cytokine response. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 42(11), 1582-1595. https://doi.org/10.1111/j.1365-2222.2012.04063.x

Trichuris suis ova therapy for allergic rhinitis does not affect allergen-specific cytokine responses despite a parasite-specific cytokine response. / Bourke, C.D.; Mutapi, F.; Nausch, N. et al.
In: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, Vol. 42, No. 11, 2012, p. 1582-1595.

Research output: Contribution to journal › Journal article › Research › peer-review

Bourke, CD, Mutapi, F, Nausch, N, Photiou, DMF, Poulsen, LK, Kristensen, B, Arnved, J, Rønborg, S, Roepstorff, AK, Thamsborg, SM , Kapel, CMO, Melbye, M & Bager, P 2012, 'Trichuris suis ova therapy for allergic rhinitis does not affect allergen-specific cytokine responses despite a parasite-specific cytokine response', Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, vol. 42, no. 11, pp. 1582-1595. https://doi.org/10.1111/j.1365-2222.2012.04063.x

Bourke CD, Mutapi F, Nausch N, Photiou DMF, Poulsen LK, Kristensen B et al. Trichuris suis ova therapy for allergic rhinitis does not affect allergen-specific cytokine responses despite a parasite-specific cytokine response. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 2012;42(11):1582-1595. doi: 10.1111/j.1365-2222.2012.04063.x

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abstract = "Parasitic helminths have been shown to reduce inflammation in most experimental models of allergic disease, and this effect is mediated via cytokine responses. However, in humans, the effects of controlled helminth infection on cytokine responses during allergy have not been studied.",

author = "C.D. Bourke and F. Mutapi and N. Nausch and D.M.F. Photiou and Poulsen, {Lars K.} and B. Kristensen and J. Arnved and S. R{\o}nborg and Roepstorff, {Allan Knud} and Thamsborg, {Stig Milan} and Kapel, {Christian Moliin Outzen} and Martin Melbye and Palle Bager",

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AU - Photiou, D.M.F.

AU - Poulsen, Lars K.

AU - Kristensen, B.

AU - Arnved, J.

AU - Rønborg, S.

AU - Roepstorff, Allan Knud

AU - Thamsborg, Stig Milan

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AU - Melbye, Martin

AU - Bager, Palle

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DO - 10.1111/j.1365-2222.2012.04063.x

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