Evaluating the dosimetric effect of intra-fractional variations in deep inspiration breath-hold radiotherapy - a proof-of-concept study

K Håkansson, M Josipovic, W Ottosson, C P Behrens, I R Vogelius, G Persson

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Abstract

Deep inspiration breath-hold (DIBH) for radiotherapy (RT) can mitigate breathing motion [Citation1–3], improve cone-beam computed tomography (CBCT) image quality [Citation4] and create a favorable anatomy regarding dose to organs at risk (OARs) [Citation1,Citation5–8]. Initial concerns about patient compliance [Citation9] have been reconsidered, as both spirometry based and voluntary, optical tracking based DIBH technique are tolerated by most patients [Citation3,Citation7,Citation10,Citation11]. However, reproducibility and dosimetric benefit vary between patients, so a method for individual assessment is warranted. It is desirable to supplement geometrical/anatomical evaluation of the reproducibility with an estimate of the dosimetric effect of an observed variation in DIBH level.

We provide a method to evaluate the dosimetric effect of intra-fractional variation in DIBH levels on a patient- and treatment plan specific level.
Original languageEnglish
JournalActa Oncologica
Volume62
Issue number10
Pages (from-to)1246-1250
Number of pages5
ISSN1100-1704
DOIs
Publication statusPublished - 2023

Keywords

  • Humans
  • Radiometry
  • Radiotherapy Dosage
  • Breath Holding
  • Radiotherapy Planning, Computer-Assisted
  • Heart
  • Unilateral Breast Neoplasms

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