Evaluation of 4-[18F]fluorobenzoyl-FALGEA-NH2 as a positron emission tomography tracer for epidermal growth factor receptor mutation variant III imaging in cancer

Charlotte Lund Denholt; Tina Binderup; Marie-Thérése Stockhausen; Hans Skovgaard Poulsen; Mogens Spang-Thomsen; Paul Robert Hansen; Nicholas Mathew Gillings; Andreas Kjær

doi:10.1016/j.nucmedbio.2010.11.003

Evaluation of 4-[¹⁸F]fluorobenzoyl-FALGEA-NH₂ as a positron emission tomography tracer for epidermal growth factor receptor mutation variant III imaging in cancer

Charlotte Lund Denholt, Tina Binderup, Marie-Thérése Stockhausen, Hans Skovgaard Poulsen, Mogens Spang-Thomsen, Paul Robert Hansen, Nicholas Mathew Gillings, Andreas Kjær

Research output: Contribution to journal › Journal article › Research › peer-review

16 Citations (Scopus)

Abstract

This study describes the radiosynthesis, in vitro and in vivo evaluation of the novel small peptide radioligand, 4-[(18)F]fluorobenzoyl-Phe-Ala-Leu-Gly-Glu-Ala-NH(2,) ([(18)F]FBA-FALGEA-NH(2)) as a positron emission tomography (PET) tracer for imaging of the cancer specific epidermal growth factor receptor (EGFR) variant III mutation, EGFRvIII.

Original language	English
Journal	Nuclear Medicine and Biology
Volume	38
Issue number	4
Pages (from-to)	509-515
Number of pages	7
ISSN	0969-8051
DOIs	https://doi.org/10.1016/j.nucmedbio.2010.11.003
Publication status	Published - 2011

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10.1016/j.nucmedbio.2010.11.003

Cite this

Denholt, C. L., Binderup, T., Stockhausen, M-T., Poulsen, H. S., Spang-Thomsen, M., Hansen, P. R., Gillings, N. M., & Kjær, A. (2011). Evaluation of 4-[¹⁸F]fluorobenzoyl-FALGEA-NH₂ as a positron emission tomography tracer for epidermal growth factor receptor mutation variant III imaging in cancer. Nuclear Medicine and Biology, 38(4), 509-515. https://doi.org/10.1016/j.nucmedbio.2010.11.003

Evaluation of 4-[¹⁸F]fluorobenzoyl-FALGEA-NH₂ as a positron emission tomography tracer for epidermal growth factor receptor mutation variant III imaging in cancer. / Denholt, Charlotte Lund; Binderup, Tina; Stockhausen, Marie-Thérése; Poulsen, Hans Skovgaard; Spang-Thomsen, Mogens; Hansen, Paul Robert; Gillings, Nicholas Mathew; Kjær, Andreas.

In: Nuclear Medicine and Biology, Vol. 38, No. 4, 2011, p. 509-515.

Research output: Contribution to journal › Journal article › Research › peer-review

Denholt, CL, Binderup, T, Stockhausen, M-T, Poulsen, HS, Spang-Thomsen, M, Hansen, PR, Gillings, NM & Kjær, A 2011, 'Evaluation of 4-[¹⁸F]fluorobenzoyl-FALGEA-NH₂ as a positron emission tomography tracer for epidermal growth factor receptor mutation variant III imaging in cancer', Nuclear Medicine and Biology, vol. 38, no. 4, pp. 509-515. https://doi.org/10.1016/j.nucmedbio.2010.11.003

Denholt, Charlotte Lund ; Binderup, Tina ; Stockhausen, Marie-Thérése ; Poulsen, Hans Skovgaard ; Spang-Thomsen, Mogens ; Hansen, Paul Robert ; Gillings, Nicholas Mathew ; Kjær, Andreas. / Evaluation of 4-[¹⁸F]fluorobenzoyl-FALGEA-NH₂ as a positron emission tomography tracer for epidermal growth factor receptor mutation variant III imaging in cancer. In: Nuclear Medicine and Biology. 2011 ; Vol. 38, No. 4. pp. 509-515.

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