Evaluation of a polyacrylamide hydrogel in the treatment of induced osteoarthritis in a goat model: a randomized controlled pilot study

Aziz Tnibar; Ann Persson; Henrik Elvang Jensen; Eiliv Lars Svalastoga; Ulrik Westrup; Fintan McEvoy; Jes Christian Knudsen; Preben Dybdahl Thomsen; Lise Charlotte Berg; Stine Jacobsen; L.H. Christensen

doi:10.1016/j.joca.2014.02.906

Evaluation of a polyacrylamide hydrogel in the treatment of induced osteoarthritis in a goat model: a randomized controlled pilot study

Aziz Tnibar, Ann Persson, Henrik Elvang Jensen, Eiliv Lars Svalastoga, Ulrik Westrup, Fintan McEvoy, Jes Christian Knudsen, Preben Dybdahl Thomsen, Lise Charlotte Berg, Stine Jacobsen, L.H. Christensen

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

Abstract

Polyacrylamide hydrogel (PAAG) is an inert, non-degradable, non-immunogenic polymer gel with high viscoelasticity consisting of 97.5% sterile water and 2.5% cross-linked polyacrylamide. Its biocompatibility in soft tissues has been demonstrated. PAAG has recently been tested for the treatment of osteoarthritis (OA) in horses with highly encouraging results; however no standardized experimental studies have been done to explore its efficacy. The purpose of this study was to evaluate PAAG in the treatment of induced OA in a goat model

Original language	English
Article number	871
Journal	Osteoarthritis and Cartilage
Volume	22, Supplement
Pages (from-to)	S477
Number of pages	1
ISSN	1063-4584
DOIs	https://doi.org/10.1016/j.joca.2014.02.906
Publication status	Published - 2014
Event	2014- world congress on osteoarthritis -oarsi - Paris, France Duration: 24 Apr 2014 → 27 Apr 2014

Conference

Conference	2014- world congress on osteoarthritis -oarsi
Country/Territory	France
City	Paris
Period	24/04/2014 → 27/04/2014

Keywords

Faculty of Health and Medical Sciences

Access to Document

10.1016/j.joca.2014.02.906

Cite this

Tnibar, A., Persson, A., Jensen, H. E., Svalastoga, E. L., Westrup, U., McEvoy, F., Knudsen, J. C., Thomsen, P. D., Berg, L. C., Jacobsen, S., & Christensen, L. H. (2014). Evaluation of a polyacrylamide hydrogel in the treatment of induced osteoarthritis in a goat model: a randomized controlled pilot study. Osteoarthritis and Cartilage, 22, Supplement, S477. [871]. https://doi.org/10.1016/j.joca.2014.02.906

Evaluation of a polyacrylamide hydrogel in the treatment of induced osteoarthritis in a goat model : a randomized controlled pilot study. / Tnibar, Aziz; Persson, Ann; Jensen, Henrik Elvang ; Svalastoga, Eiliv Lars; Westrup, Ulrik; McEvoy, Fintan; Knudsen, Jes Christian; Thomsen, Preben Dybdahl ; Berg, Lise Charlotte ; Jacobsen, Stine; Christensen, L.H.

In: Osteoarthritis and Cartilage, Vol. 22, Supplement, 871, 2014, p. S477.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

Tnibar, A, Persson, A, Jensen, HE , Svalastoga, EL, Westrup, U, McEvoy, F, Knudsen, JC, Thomsen, PD , Berg, LC , Jacobsen, S & Christensen, LH 2014, 'Evaluation of a polyacrylamide hydrogel in the treatment of induced osteoarthritis in a goat model: a randomized controlled pilot study', Osteoarthritis and Cartilage, vol. 22, Supplement, 871, pp. S477. https://doi.org/10.1016/j.joca.2014.02.906

Tnibar, Aziz ; Persson, Ann ; Jensen, Henrik Elvang ; Svalastoga, Eiliv Lars ; Westrup, Ulrik ; McEvoy, Fintan ; Knudsen, Jes Christian ; Thomsen, Preben Dybdahl ; Berg, Lise Charlotte ; Jacobsen, Stine ; Christensen, L.H. / Evaluation of a polyacrylamide hydrogel in the treatment of induced osteoarthritis in a goat model : a randomized controlled pilot study. In: Osteoarthritis and Cartilage. 2014 ; Vol. 22, Supplement. pp. S477.

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abstract = "Polyacrylamide hydrogel (PAAG) is an inert, non-degradable, non-immunogenic polymer gel with high viscoelasticity consisting of 97.5% sterile water and 2.5% cross-linked polyacrylamide. Its biocompatibility in soft tissues has been demonstrated. PAAG has recently been tested for the treatment of osteoarthritis (OA) in horses with highly encouraging results; however no standardized experimental studies have been done to explore its efficacy. The purpose of this study was to evaluate PAAG in the treatment of induced OA in a goat model",

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AU - Westrup, Ulrik

AU - McEvoy, Fintan

AU - Knudsen, Jes Christian

AU - Thomsen, Preben Dybdahl

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AB - Polyacrylamide hydrogel (PAAG) is an inert, non-degradable, non-immunogenic polymer gel with high viscoelasticity consisting of 97.5% sterile water and 2.5% cross-linked polyacrylamide. Its biocompatibility in soft tissues has been demonstrated. PAAG has recently been tested for the treatment of osteoarthritis (OA) in horses with highly encouraging results; however no standardized experimental studies have been done to explore its efficacy. The purpose of this study was to evaluate PAAG in the treatment of induced OA in a goat model

KW - Faculty of Health and Medical Sciences

KW - Goats

KW - Veterinary medicine

KW - Animal Model

KW - joint disease

KW - Osteoarthritis

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DO - 10.1016/j.joca.2014.02.906

M3 - Conference abstract in journal

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JO - Osteoarthritis and Cartilage

JF - Osteoarthritis and Cartilage

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