Expectant management of PPROM and major complications before planned delivery: A retrospective cohort study

J. M. Bendix*, H. K. Hegaard, T. Bergholt, J. Langhoff-Roos

*Corresponding author for this work

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15 Citations (Scopus)

Abstract

Women with pre-term pre-labour rupture of membranes (PPROM) 22-33 weeks gestation were included in a retrospective cohort study with a structured audit to identify risk factors of major complications following PPROM and to assess whether these complications are predictable. Of the 234 women analysed, 106 (45%) delivered within three days. Eighty-four women (36%) had at least one major complication and 45% of these complications occurred within three days. The complication rate was 64% in early PPROM before 28 weeks gestation and 11% in late PPROM at 28 weeks gestation or later. Nulliparous women had an increased risk of major complications (adjusted hazards ratio: 3.07 (95% confidence interval: 1.28-7.37)). The complication rates were highest in early PPROM and during the first three days after PPROM.Multiparous women with late PPROM, who do not deliver within the first three days, have the lowest risk of major complications and are suitable for home care.

Original languageEnglish
JournalJournal of Obstetrics and Gynaecology
Volume35
Issue number6
Pages (from-to)570-577
Number of pages8
ISSN0144-3615
DOIs
Publication statusPublished - 18 Aug 2015

Keywords

  • Chorioamnionitis
  • cord prolapse
  • general obstetrics
  • place of care
  • placental abruption
  • PPROM

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