Exploring the chemotactic attraction of Campylobacter jejuni in chicken colonization

Christina Skovgaard Vegge, Lone Brøndsted, Hanne Ingmer

    Research output: Contribution to conferenceConference abstract for conferenceResearch

    Abstract

    Campylobacter jejuni is the primary food borne bacterial pathogen in the developed world. The most important reservoir for C. jejuni is the gut of chickens, which are colonized commensally and efficiently by this organism. Predominantly the mucus filled crypts of the lower gastrointestinal tract are found to be colonized by C. jejuni, and the bacteria are expected to be attracted to this particular environment by chemotaxis. In order to explore the role of chemotaxis in C. jejuni colonization we are construction deletion mutants in the putative chemoreceptors of the sequenced strain NCTC11168. These mutants will be analyzed for their chemotatic capacity in order to investigate the chemoreceptor function and to identify matching chemoeffectors. Furthermore, selected mutants will be investigated for their ability to colonize chickens with focus on establishment, level, and persistence. Special emphasis will be held at characterizing the colonization of mucus layers.
    Original languageEnglish
    Publication date2006
    Number of pages1
    Publication statusPublished - 2006
    EventFourth symposium on food microbiology - Ebberup, Denmark
    Duration: 18 May 200619 May 2006
    Conference number: 4

    Conference

    ConferenceFourth symposium on food microbiology
    Number4
    Country/TerritoryDenmark
    CityEbberup
    Period18/05/200619/05/2006

    Cite this