Abstract
KCNQ-encoded voltage-gated potassium channels (K(v) 7) have recently been identified as important anti-constrictor elements in rodent blood vessels but the role of these channels and the effects of their modulation in human arteries remain unknown. Here, we have assessed KCNQ gene expression and function in human arteries ex vivo.
Original language | English |
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Journal | British Journal of Pharmacology |
Volume | 162 |
Issue number | 1 |
Pages (from-to) | 42-53 |
Number of pages | 12 |
ISSN | 0007-1188 |
DOIs | |
Publication status | Published - Jan 2011 |
Keywords
- Aged
- Arteries
- Female
- Humans
- Immunohistochemistry
- KCNQ Potassium Channels
- Male
- Middle Aged
- Polymerase Chain Reaction
- RNA, Messenger