Expression of matrix metalloproteinase 9 (MMP-9) and tissue inhibitor of metalloproteinases 1 (TIMP-1) by colorectal cancer cells and adjacent stroma cells--associations with histopathology and patients outcome

Søren Astrup Jensen; Ben Vainer; Annette Bartels; Nils Aage Brünner; Jens Benn Sørensen

doi:http://dx.doi.org/10.1016/j.ejca.2010.07.046

Expression of matrix metalloproteinase 9 (MMP-9) and tissue inhibitor of metalloproteinases 1 (TIMP-1) by colorectal cancer cells and adjacent stroma cells--associations with histopathology and patients outcome

Søren Astrup Jensen, Ben Vainer, Annette Bartels, Nils Aage Brünner, Jens Benn Sørensen

BSc + MSc programme

Research output: Contribution to journal › Journal article › Research › peer-review

40 Citations (Scopus)

Abstract

To elucidate cellular features accountable for colorectal cancers' (CRC) capability to invade normal tissue and to metastasize, we investigated the level of the collagenase matrix metalloproteinase 9 (MMP-9) and its physiological inhibitor tissue inhibitor of metalloproteinases 1 (TIMP-1) in cancer cells and supporting stroma cells of CRC.

Original language	English
Journal	European Journal of Cancer
Volume	46
Issue number	18
Pages (from-to)	3233-42
Number of pages	10
ISSN	0959-8049
DOIs	https://doi.org/10.1016/j.ejca.2010.07.046
Publication status	Published - 1 Dec 2010

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http://dx.doi.org/10.1016/j.ejca.2010.07.046

Cite this

Jensen, S. A., Vainer, B., Bartels, A., Brünner, N. A., & Sørensen, J. B. (2010). Expression of matrix metalloproteinase 9 (MMP-9) and tissue inhibitor of metalloproteinases 1 (TIMP-1) by colorectal cancer cells and adjacent stroma cells--associations with histopathology and patients outcome. European Journal of Cancer, 46(18), 3233-42. https://doi.org/10.1016/j.ejca.2010.07.046

Expression of matrix metalloproteinase 9 (MMP-9) and tissue inhibitor of metalloproteinases 1 (TIMP-1) by colorectal cancer cells and adjacent stroma cells--associations with histopathology and patients outcome. / Jensen, Søren Astrup; Vainer, Ben; Bartels, Annette; Brünner, Nils Aage; Sørensen, Jens Benn.

In: European Journal of Cancer, Vol. 46, No. 18, 01.12.2010, p. 3233-42.

Research output: Contribution to journal › Journal article › Research › peer-review

Jensen, SA, Vainer, B, Bartels, A, Brünner, NA & Sørensen, JB 2010, 'Expression of matrix metalloproteinase 9 (MMP-9) and tissue inhibitor of metalloproteinases 1 (TIMP-1) by colorectal cancer cells and adjacent stroma cells--associations with histopathology and patients outcome', European Journal of Cancer, vol. 46, no. 18, pp. 3233-42. https://doi.org/10.1016/j.ejca.2010.07.046

Jensen, Søren Astrup ; Vainer, Ben ; Bartels, Annette ; Brünner, Nils Aage ; Sørensen, Jens Benn. / Expression of matrix metalloproteinase 9 (MMP-9) and tissue inhibitor of metalloproteinases 1 (TIMP-1) by colorectal cancer cells and adjacent stroma cells--associations with histopathology and patients outcome. In: European Journal of Cancer. 2010 ; Vol. 46, No. 18. pp. 3233-42.

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abstract = "To elucidate cellular features accountable for colorectal cancers' (CRC) capability to invade normal tissue and to metastasize, we investigated the level of the collagenase matrix metalloproteinase 9 (MMP-9) and its physiological inhibitor tissue inhibitor of metalloproteinases 1 (TIMP-1) in cancer cells and supporting stroma cells of CRC.",

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