Abstract
The chance of a live birth after a diagnosis of secondary recurrent miscarriage (SRM) is reduced in patients who, prior to the miscarriages, gave birth to a boy and carry HLA class II alleles that efficiently present male-specific (H-Y) antigens to the immune system. Information about obstetric complications in births prior and subsequent to the SRM diagnosis is limited. The relations between maternal carriage of H-Y-restricting HLA, fetal sex, obstetric complications and prognosis are unknown.
Original language | English |
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Journal | Human Reproduction |
Volume | 25 |
Issue number | 6 |
Pages (from-to) | 1543-52 |
Number of pages | 10 |
ISSN | 0268-1161 |
DOIs | |
Publication status | Published - Jun 2010 |
Keywords
- Abortion, Habitual
- Alleles
- Denmark
- Female
- H-Y Antigen
- HLA Antigens
- Histocompatibility, Maternal-Fetal
- Humans
- Infant, Newborn
- Live Birth
- Male
- Pregnancy
- Pregnancy Complications
- Registries
- Risk Factors
- Statistics, Nonparametric