Fungal innate immunity induced by bacterial microbe-associated molecular patterns (MAMPs)

Simon Ip Cho, Thomas Sundelin, Gitte Erbs, H Corby Kistler, Mari-Anne Newman, Stefan Olsson

Research output: Contribution to journalJournal articleResearchpeer-review

31 Citations (Scopus)

Abstract

Plants and animals detect bacterial presence through Microbe-Associated Molecular Patterns (MAMPs) which induce an innate immune response. The field of fungal-bacterial interaction at the molecular level is still in its infancy and little is known about MAMPs and their detection by fungi. Exposing Fusarium graminearum to bacterial MAMPs led to increased fungal membrane hyperpolarization, a putative defense response, and a range of transcriptional responses. The fungus reacted with a different transcript profile to each of the three tested MAMPs, although a core set of genes related to energy generation, transport, amino acid production, secondary metabolism, and especially iron uptake were detected for all three. Half of the genes related to iron uptake were predicted MirA type transporters that potentially take up bacterial siderophores. These quick responses can be viewed as a preparation for further interactions with beneficial or pathogenic bacteria, and constitute a fungal innate immune response with similarities to those of plants and animals.

Original languageEnglish
JournalG3: Genes, Genomes, Genetics (Bethesda)
Volume6
Issue number6
Pages (from-to)1585-1595
Number of pages11
ISSN2160-1836
DOIs
Publication statusPublished - 2016

Keywords

  • Journal Article

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