Genetic associations with valvular calcification and aortic stenosis

George Thanassoulis; Catherine Y Campbell; David S Owens; J Gustav Smith; Albert V Smith; Gina M Peloso; Kathleen F Kerr; Sonali Pechlivanis; Matthew J Budoff; Tamara B Harris; Rajeev Malhotra; Kevin D O'Brien; Pia R Kamstrup; Børge G Nordestgaard; Anne Tybjaerg-Hansen; Matthew A Allison; Thor Aspelund; Michael H Criqui; Susan R Heckbert; Shih-Jen Hwang; Yongmei Liu; Marketa Sjogren; Jesper van der Pals; Hagen Kälsch; Thomas W Mühleisen; Markus M Nöthen; L Adrienne Cupples; Muriel Caslake; Emanuele Di Angelantonio; John Danesh; Jerome I Rotter; Sigurdur Sigurdsson; Quenna Wong; Raimund Erbel; Sekar Kathiresan; Olle Melander; Vilmundur Gudnason; Christopher J O'Donnell; Wendy S Post; CHARGE Extracoronary Calcium Working Group

doi:10.1056/NEJMoa1109034

Genetic associations with valvular calcification and aortic stenosis

George Thanassoulis, Catherine Y Campbell, David S Owens, J Gustav Smith, Albert V Smith, Gina M Peloso, Kathleen F Kerr, Sonali Pechlivanis, Matthew J Budoff, Tamara B Harris, Rajeev Malhotra, Kevin D O'Brien, Pia R Kamstrup, Børge G Nordestgaard, Anne Tybjaerg-Hansen, Matthew A Allison, Thor Aspelund, Michael H Criqui, Susan R Heckbert, Shih-Jen HwangYongmei Liu, Marketa Sjogren, Jesper van der Pals, Hagen Kälsch, Thomas W Mühleisen, Markus M Nöthen, L Adrienne Cupples, Muriel Caslake, Emanuele Di Angelantonio, John Danesh, Jerome I Rotter, Sigurdur Sigurdsson, Quenna Wong, Raimund Erbel, Sekar Kathiresan, Olle Melander, Vilmundur Gudnason, Christopher J O'Donnell, Wendy S Post, CHARGE Extracoronary Calcium Working Group

Research output: Contribution to journal › Journal article › Research › peer-review

762 Citations (Scopus)

Abstract

Limited information is available regarding genetic contributions to valvular calcification, which is an important precursor of clinical valve disease.

Original language	English
Journal	New England Journal of Medicine
Volume	368
Issue number	6
Pages (from-to)	503-12
Number of pages	10
ISSN	0028-4793
DOIs	https://doi.org/10.1056/NEJMoa1109034
Publication status	Published - 7 Feb 2013

Access to Document

10.1056/NEJMoa1109034

Cite this

Thanassoulis, G., Campbell, C. Y., Owens, D. S., Smith, J. G., Smith, A. V., Peloso, G. M., Kerr, K. F., Pechlivanis, S., Budoff, M. J., Harris, T. B., Malhotra, R., O'Brien, K. D., Kamstrup, P. R., Nordestgaard, B. G., Tybjaerg-Hansen, A., Allison, M. A., Aspelund, T., Criqui, M. H., Heckbert, S. R., ... CHARGE Extracoronary Calcium Working Group (2013). Genetic associations with valvular calcification and aortic stenosis. New England Journal of Medicine, 368(6), 503-12. https://doi.org/10.1056/NEJMoa1109034

Genetic associations with valvular calcification and aortic stenosis. / Thanassoulis, George; Campbell, Catherine Y; Owens, David S; Smith, J Gustav; Smith, Albert V; Peloso, Gina M; Kerr, Kathleen F; Pechlivanis, Sonali; Budoff, Matthew J; Harris, Tamara B; Malhotra, Rajeev; O'Brien, Kevin D; Kamstrup, Pia R ; Nordestgaard, Børge G ; Tybjaerg-Hansen, Anne; Allison, Matthew A; Aspelund, Thor; Criqui, Michael H; Heckbert, Susan R; Hwang, Shih-Jen; Liu, Yongmei; Sjogren, Marketa; van der Pals, Jesper; Kälsch, Hagen; Mühleisen, Thomas W; Nöthen, Markus M; Cupples, L Adrienne; Caslake, Muriel; Di Angelantonio, Emanuele; Danesh, John; Rotter, Jerome I; Sigurdsson, Sigurdur; Wong, Quenna; Erbel, Raimund; Kathiresan, Sekar; Melander, Olle; Gudnason, Vilmundur; O'Donnell, Christopher J; Post, Wendy S; CHARGE Extracoronary Calcium Working Group.

In: New England Journal of Medicine, Vol. 368, No. 6, 07.02.2013, p. 503-12.

Research output: Contribution to journal › Journal article › Research › peer-review

Thanassoulis, G, Campbell, CY, Owens, DS, Smith, JG, Smith, AV, Peloso, GM, Kerr, KF, Pechlivanis, S, Budoff, MJ, Harris, TB, Malhotra, R, O'Brien, KD, Kamstrup, PR , Nordestgaard, BG , Tybjaerg-Hansen, A, Allison, MA, Aspelund, T, Criqui, MH, Heckbert, SR, Hwang, S-J, Liu, Y, Sjogren, M, van der Pals, J, Kälsch, H, Mühleisen, TW, Nöthen, MM, Cupples, LA, Caslake, M, Di Angelantonio, E, Danesh, J, Rotter, JI, Sigurdsson, S, Wong, Q, Erbel, R, Kathiresan, S, Melander, O, Gudnason, V, O'Donnell, CJ, Post, WS & CHARGE Extracoronary Calcium Working Group 2013, 'Genetic associations with valvular calcification and aortic stenosis', New England Journal of Medicine, vol. 368, no. 6, pp. 503-12. https://doi.org/10.1056/NEJMoa1109034

Thanassoulis, George ; Campbell, Catherine Y ; Owens, David S ; Smith, J Gustav ; Smith, Albert V ; Peloso, Gina M ; Kerr, Kathleen F ; Pechlivanis, Sonali ; Budoff, Matthew J ; Harris, Tamara B ; Malhotra, Rajeev ; O'Brien, Kevin D ; Kamstrup, Pia R ; Nordestgaard, Børge G ; Tybjaerg-Hansen, Anne ; Allison, Matthew A ; Aspelund, Thor ; Criqui, Michael H ; Heckbert, Susan R ; Hwang, Shih-Jen ; Liu, Yongmei ; Sjogren, Marketa ; van der Pals, Jesper ; Kälsch, Hagen ; Mühleisen, Thomas W ; Nöthen, Markus M ; Cupples, L Adrienne ; Caslake, Muriel ; Di Angelantonio, Emanuele ; Danesh, John ; Rotter, Jerome I ; Sigurdsson, Sigurdur ; Wong, Quenna ; Erbel, Raimund ; Kathiresan, Sekar ; Melander, Olle ; Gudnason, Vilmundur ; O'Donnell, Christopher J ; Post, Wendy S ; CHARGE Extracoronary Calcium Working Group. / Genetic associations with valvular calcification and aortic stenosis. In: New England Journal of Medicine. 2013 ; Vol. 368, No. 6. pp. 503-12.

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abstract = "Limited information is available regarding genetic contributions to valvular calcification, which is an important precursor of clinical valve disease.",

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AU - Nöthen, Markus M

AU - Cupples, L Adrienne

AU - Caslake, Muriel

AU - Di Angelantonio, Emanuele

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