Genome-wide association study of genetic variants in LPS-stimulated IL-6, IL-8, IL-10, IL-1ra and TNF-α cytokine response in a Danish Cohort

Margit Hørup Larsen; Anders Albrechtsen; Lise Wegner Thørner; Thomas Werge; Thomas Hansen; Ulrik Gether; Eva Haastrup; Henrik Ullum

doi:10.1371/journal.pone.0066262

Genome-wide association study of genetic variants in LPS-stimulated IL-6, IL-8, IL-10, IL-1ra and TNF-α cytokine response in a Danish Cohort

Margit Hørup Larsen, Anders Albrechtsen, Lise Wegner Thørner, Thomas Werge, Thomas Hansen, Ulrik Gether, Eva Haastrup, Henrik Ullum

Research output: Contribution to journal › Journal article › Research › peer-review

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Abstract

Cytokine response plays a vital role in various human lipopolysaccharide (LPS) infectious and inflammatory diseases. This study aimed to find genetic variants that might affect the levels of LPS-induced interleukin (IL)-6, IL-8, IL-10, IL-1ra and tumor necrosis factor (TNF)-α cytokine production.

Original language	English
Article number	e66262
Journal	PLOS ONE
Volume	8
Issue number	6
Number of pages	6
ISSN	1932-6203
DOIs	https://doi.org/10.1371/journal.pone.0066262
Publication status	Published - 2013

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10.1371/journal.pone.0066262

Genome-Wide Association Study of Genetic Variants in LPS-Stimulated IL-6, IL-8, IL-10, IL-1ra and TNF-α Cytokine Response in a Danish CohortFinal published version, 557 KB

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Genome-wide association study of genetic variants in LPS-stimulated IL-6, IL-8, IL-10, IL-1ra and TNF-α cytokine response in a Danish Cohort. / Larsen, Margit Hørup; Albrechtsen, Anders; Thørner, Lise Wegner; Werge, Thomas; Hansen, Thomas; Gether, Ulrik; Haastrup, Eva; Ullum, Henrik.

In: PLOS ONE, Vol. 8, No. 6, e66262, 2013.

Research output: Contribution to journal › Journal article › Research › peer-review

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