High-dose-rate mold brachytherapy for mandibular gingival squamous cell carcinoma in outpatient setting – Initial case report

A. Takeshita, H. Shimamoto, Y. Uchimoto, T. Tsujimoto, T. Miyamoto, S. Kreiborg, S. M. Mallya, M. Oda, T. Hirata, K. Ogawa, H. Shiomi, S. Murakami

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

Brachytherapy is often used to treat oral cancer, as it generally yields a good outcome
with little oral function loss. In particular, mold brachytherapy is ideally suited for
superficial oral cases, such as cancers developing on the gingiva, palate, or buccal
mucosa, with little to no bone involvement and thin tissue thickness. Mold
brachytherapy including that at a high-dose-rate (HDR) is used to treat gingival cancer,
though hospitalization is the typical treatment setting. Reported here are details of
HDR mold brachytherapy performed in an outpatient setting for a mandibular gingival
case of squamous cell carcinoma (SCC). Mandibular gingival SCC in a 71-year-old man
was treated as an outpatient using HDR mold brachytherapy (54 Gy in 9 fractions, 5
days). After receiving mold treatment for thirty months, there was no sign of
recurrence or metastasis. To our knowledge, this is the first report of HDR mold
brachytherapy in an outpatient setting for treating mandibular gingival cancer.
Original languageEnglish
JournalIranian Journal of Radiation Research
Volume21
Issue number4
Pages (from-to)849-853
ISSN1728-4554
DOIs
Publication statusPublished - 2023

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