Abstract
Extensive transcription of non-coding RNAs has been detected in eukaryotic genomes and is thought to constitute an additional layer in the regulation of gene expression. Despite this role, their transcription through the cell cycle has not been studied; genome-wide approaches have only focused on protein-coding genes. To explore the complex transcriptome architecture underlying the budding yeast cell cycle, we used 8 bp tiling arrays to generate a 5 minute-resolution, strand-specific expression atlas of the whole genome.
Original language | English |
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Journal | Genome Biology (Online Edition) |
Volume | 11 |
Issue number | 3 |
Pages (from-to) | R24 |
ISSN | 1474-7596 |
DOIs | |
Publication status | Published - 1 Jan 2010 |
Keywords
- Gene Expression Profiling
- Gene Expression Regulation, Fungal
- Genome, Fungal
- Genomics
- Mitosis
- RNA, Antisense
- RNA, Untranslated
- Saccharomyces cerevisiae