Hollow fiber-based liquid phase microextraction followed by analytical instrumental techniques for quantitative analysis of heavy metal ions and pharmaceuticals

Wajid Ali Khan, Muhammad Balal Arain, Yadollah Yamini, Nasrullah Shah, Tasneem Gul Kazi, Stig Pedersen-Bjergaard*, Mohammad Tajik

*Corresponding author for this work

Research output: Contribution to journalReviewpeer-review

113 Citations (Scopus)
16 Downloads (Pure)

Abstract

Hollow-fiber liquid-phase microextraction (HF-LPME) and electromembrane extraction (EME) are miniaturized extraction techniques, and have been coupled with various analytical instruments for trace analysis of heavy metals, drugs and other organic compounds, in recent years. HF-LPME and EME provide high selectivity, efficient sample cleanup and enrichment, and reduce the consumption of organic solvents to a few micro-liters per sample. HF-LPME and EME are compatible with different analytical instruments for chromatography, electrophoresis, atomic spectroscopy, mass spectrometry, and electrochemical detection. HF-LPME and EME have gained significant popularity during the recent years. This review focuses on hollow fiber based techniques (especially HF-LPME and EME) of heavy metals and pharmaceuticals (published 2017 to May 2019), and their combinations with atomic spectroscopy, UV-VIS spectrophotometry, high performance liquid chromatography, gas chromatography, capillary electrophoresis, and voltammetry.

Original languageEnglish
JournalJournal of Pharmaceutical Analysis
Volume10
Issue number2
Pages (from-to)109-122
Number of pages14
ISSN2095-1779
DOIs
Publication statusPublished - 2020

Keywords

  • Electromembrane extraction
  • Heavy metals
  • Hollow fiber liquid phase microextraction
  • Instrumental techniques
  • Pharmaceuticals

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