Human genetic polymorphisms in the Knops blood group are not associated with a protective advantage against Plasmodium falciparum malaria in Southern Ghana

Helle H Hansson; Jørgen A Kurtzhals; Bamenla Q Goka; Onike P Rodriques; Francis N Nkrumah; Thor G Theander; Ib Christian Bygbjerg; Michael Alifrangis

doi:10.1186/1475-2875-12-400

Human genetic polymorphisms in the Knops blood group are not associated with a protective advantage against Plasmodium falciparum malaria in Southern Ghana

Helle H Hansson, Jørgen A Kurtzhals, Bamenla Q Goka, Onike P Rodriques, Francis N Nkrumah, Thor G Theander, Ib Christian Bygbjerg, Michael Alifrangis

Research output: Contribution to journal › Journal article › Research › peer-review

19 Citations (Scopus)

Abstract

The complex interactions between the human host and the Plasmodium falciparum parasite and the factors influencing severity of disease are still not fully understood. Human single nucleotide polymorphisms SNPs associated with Knops blood group system; carried by complement receptor 1 may be associated with the pathology of P. falciparum malaria, and susceptibility to disease.

Original language	English
Journal	Malaria Journal
Volume	12
Issue number	1
Pages (from-to)	400
ISSN	1475-2875
DOIs	https://doi.org/10.1186/1475-2875-12-400
Publication status	Published - 7 Nov 2013

Access to Document

10.1186/1475-2875-12-400

Cite this

@article{36d61aa9b7864e80a9a2755f9b15b4c9,

title = "Human genetic polymorphisms in the Knops blood group are not associated with a protective advantage against Plasmodium falciparum malaria in Southern Ghana",

abstract = "The complex interactions between the human host and the Plasmodium falciparum parasite and the factors influencing severity of disease are still not fully understood. Human single nucleotide polymorphisms SNPs associated with Knops blood group system; carried by complement receptor 1 may be associated with the pathology of P. falciparum malaria, and susceptibility to disease.",

author = "Hansson, {Helle H} and Kurtzhals, {J{\o}rgen A} and Goka, {Bamenla Q} and Rodriques, {Onike P} and Nkrumah, {Francis N} and Theander, {Thor G} and Bygbjerg, {Ib Christian} and Michael Alifrangis",

year = "2013",

month = nov,

day = "7",

doi = "10.1186/1475-2875-12-400",

language = "English",

volume = "12",

pages = "400",

journal = "Malaria Journal",

issn = "1475-2875",

publisher = "BioMed Central",

number = "1",

}

TY - JOUR

T1 - Human genetic polymorphisms in the Knops blood group are not associated with a protective advantage against Plasmodium falciparum malaria in Southern Ghana

AU - Hansson, Helle H

AU - Kurtzhals, Jørgen A

AU - Goka, Bamenla Q

AU - Rodriques, Onike P

AU - Nkrumah, Francis N

AU - Theander, Thor G

AU - Bygbjerg, Ib Christian

AU - Alifrangis, Michael

PY - 2013/11/7

Y1 - 2013/11/7

N2 - The complex interactions between the human host and the Plasmodium falciparum parasite and the factors influencing severity of disease are still not fully understood. Human single nucleotide polymorphisms SNPs associated with Knops blood group system; carried by complement receptor 1 may be associated with the pathology of P. falciparum malaria, and susceptibility to disease.

AB - The complex interactions between the human host and the Plasmodium falciparum parasite and the factors influencing severity of disease are still not fully understood. Human single nucleotide polymorphisms SNPs associated with Knops blood group system; carried by complement receptor 1 may be associated with the pathology of P. falciparum malaria, and susceptibility to disease.

U2 - 10.1186/1475-2875-12-400

DO - 10.1186/1475-2875-12-400

M3 - Journal article

C2 - 24200236

SN - 1475-2875

VL - 12

SP - 400

JO - Malaria Journal

JF - Malaria Journal

IS - 1

ER -